Ahmed-Belkacem A - Search Results

1

Discovery of naturally occurring aurones that are potent allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase.

Haudecoeur R, Ahmed-Belkacem A, Yi W, Fortuné A, Brillet R, Belle C, Nicolle E, Pallier C, Pawlotsky JM, Boumendjel A. Haudecoeur R, et al. J Med Chem. 2011 Aug 11;54(15):5395-402. doi: 10.1021/jm200242p. Epub 2011 Jul 6. J Med Chem. 2011. PMID: 21699179 Free PMC article.

2

Inhibitors of cancer cell multidrug resistance mediated by breast cancer resistance protein (BCRP/ABCG2).

Ahmed-Belkacem A, Pozza A, Macalou S, Pérez-Victoria JM, Boumendjel A, Di Pietro A. Ahmed-Belkacem A, et al. Anticancer Drugs. 2006 Mar;17(3):239-43. doi: 10.1097/00001813-200603000-00001. Anticancer Drugs. 2006. PMID: 16520651 Review.

3

Acridone derivatives: design, synthesis, and inhibition of breast cancer resistance protein ABCG2.

Boumendjel A, Macalou S, Ahmed-Belkacem A, Blanc M, Di Pietro A. Boumendjel A, et al. Bioorg Med Chem. 2007 Apr 15;15(8):2892-7. doi: 10.1016/j.bmc.2007.02.017. Epub 2007 Feb 13. Bioorg Med Chem. 2007. PMID: 17317193

4

Nonprenylated rotenoids, a new class of potent breast cancer resistance protein inhibitors.

Ahmed-Belkacem A, Macalou S, Borrelli F, Capasso R, Fattorusso E, Taglialatela-Scafati O, Di Pietro A. Ahmed-Belkacem A, et al. J Med Chem. 2007 Apr 19;50(8):1933-8. doi: 10.1021/jm061450q. Epub 2007 Mar 7. J Med Chem. 2007. PMID: 17341062

5

QSAR analysis and molecular modeling of ABCG2-specific inhibitors.

Nicolle E, Boumendjel A, Macalou S, Genoux E, Ahmed-Belkacem A, Carrupt PA, Di Pietro A. Nicolle E, et al. Adv Drug Deliv Rev. 2009 Jan 31;61(1):34-46. doi: 10.1016/j.addr.2008.10.004. Epub 2008 Dec 16. Adv Drug Deliv Rev. 2009. PMID: 19135106 Review.

6

Silibinin and related compounds are direct inhibitors of hepatitis C virus RNA-dependent RNA polymerase.

Ahmed-Belkacem A, Ahnou N, Barbotte L, Wychowski C, Pallier C, Brillet R, Pohl RT, Pawlotsky JM. Ahmed-Belkacem A, et al. Gastroenterology. 2010 Mar;138(3):1112-22. doi: 10.1053/j.gastro.2009.11.053. Epub 2009 Dec 4. Gastroenterology. 2010. PMID: 19962982 Free article.

7

Characterization of V36C, a novel amino acid substitution conferring hepatitis C virus (HCV) resistance to telaprevir, a potent peptidomimetic inhibitor of HCV protease.

Barbotte L, Ahmed-Belkacem A, Chevaliez S, Soulier A, Hézode C, Wajcman H, Bartels DJ, Zhou Y, Ardzinski A, Mani N, Rao BG, George S, Kwong A, Pawlotsky JM. Barbotte L, et al. Antimicrob Agents Chemother. 2010 Jun;54(6):2681-3. doi: 10.1128/AAC.01796-09. Epub 2010 Apr 5. Antimicrob Agents Chemother. 2010. PMID: 20368394 Free PMC article.

8

Structure-activity relationships in the development of allosteric hepatitis C virus RNA-dependent RNA polymerase inhibitors: ten years of research.

Haudecoeur R, Peuchmaur M, Ahmed-Belkacem A, Pawlotsky JM, Boumendjel A. Haudecoeur R, et al. Med Res Rev. 2013 Sep;33(5):934-84. doi: 10.1002/med.21271. Epub 2012 Aug 14. Med Res Rev. 2013. PMID: 22893620 Review.

9

B-ring modified aurones as promising allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase.

Meguellati A, Ahmed-Belkacem A, Yi W, Haudecoeur R, Crouillère M, Brillet R, Pawlotsky JM, Boumendjel A, Peuchmaur M. Meguellati A, et al. Eur J Med Chem. 2014 Jun 10;80:579-92. doi: 10.1016/j.ejmech.2014.04.005. Epub 2014 Apr 4. Eur J Med Chem. 2014. PMID: 24835816

10

Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: a new mechanism for antiviral intervention.

Ahmed-Belkacem A, Guichou JF, Brillet R, Ahnou N, Hernandez E, Pallier C, Pawlotsky JM. Ahmed-Belkacem A, et al. Nucleic Acids Res. 2014 Aug;42(14):9399-409. doi: 10.1093/nar/gku632. Epub 2014 Jul 22. Nucleic Acids Res. 2014. PMID: 25053847 Free PMC article.

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