Allan PW - Search Results

1

The crystal structure of Streptococcus pyogenes uridine phosphorylase reveals a distinct subfamily of nucleoside phosphorylases.

Tran TH, Christoffersen S, Allan PW, Parker WB, Piskur J, Serra I, Terreni M, Ealick SE. Tran TH, et al. Among authors: allan pw. Biochemistry. 2011 Aug 2;50(30):6549-58. doi: 10.1021/bi200707z. Epub 2011 Jul 8. Biochemistry. 2011. PMID: 21707079 Free PMC article.

2

Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.

Bennett EM, Li C, Allan PW, Parker WB, Ealick SE. Bennett EM, et al. Among authors: allan pw. J Biol Chem. 2003 Nov 21;278(47):47110-8. doi: 10.1074/jbc.M304622200. Epub 2003 Aug 21. J Biol Chem. 2003. PMID: 12937174 Free article.

3

Structure of grouper iridovirus purine nucleoside phosphorylase.

Kang YN, Zhang Y, Allan PW, Parker WB, Ting JW, Chang CY, Ealick SE. Kang YN, et al. Among authors: allan pw. Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):155-62. doi: 10.1107/S0907444909048276. Epub 2010 Jan 22. Acta Crystallogr D Biol Crystallogr. 2010. PMID: 20124695 Free PMC article.

4

Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.

Bennett EM, Anand R, Allan PW, Hassan AE, Hong JS, Levasseur DN, McPherson DT, Parker WB, Secrist JA 3rd, Sorscher EJ, Townes TM, Waud WR, Ealick SE. Bennett EM, et al. Among authors: allan pw. Chem Biol. 2003 Dec;10(12):1173-81. doi: 10.1016/j.chembiol.2003.11.008. Chem Biol. 2003. PMID: 14700625

5

The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors.

Parker WB, Allan PW, Waud WR, Hong J, Gilbert-Ross M, Achyut BR, Joshi D, Behbahani T, Rab R, Ealick SE, Sorscher EJ. Parker WB, et al. Among authors: allan pw. Cancer Chemother Pharmacol. 2020 Mar;85(3):573-583. doi: 10.1007/s00280-019-04018-7. Epub 2020 Jan 8. Cancer Chemother Pharmacol. 2020. PMID: 31915968 Free PMC article.

6

6-Methylpurine derived sugar modified nucleosides: Synthesis and evaluation of their substrate activity with purine nucleoside phosphorylases.

Hassan AE, Abou-Elkhair RA, Parker WB, Allan PW, Secrist JA 3rd. Hassan AE, et al. Among authors: allan pw. Bioorg Chem. 2016 Apr;65:9-16. doi: 10.1016/j.bioorg.2015.12.006. Epub 2015 Dec 24. Bioorg Chem. 2016. PMID: 26745284

7

Design and evaluation of 5'-modified nucleoside analogs as prodrugs for an E. coli purine nucleoside phosphorylase mutant.

Parker WB, Allan PW, Ealick SE, Sorscher EJ, Hassan AE, Silamkoti AV, Fowler AT, Waud WR, Secrist JA 3rd. Parker WB, et al. Among authors: allan pw. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):387-92. doi: 10.1081/ncn-200059807. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16247956

8

Gene therapy of cancer: activation of nucleoside prodrugs with E. coli purine nucleoside phosphorylase.

Secrist JA 3rd, Parker WB, Allan PW, Bennett LL Jr, Waud WR, Truss JW, Fowler AT, Montgomery JA, Ealick SE, Wells AH, Gillespie GY, Gadi VK, Sorscher EJ. Secrist JA 3rd, et al. Among authors: allan pw. Nucleosides Nucleotides. 1999 Apr-May;18(4-5):745-57. doi: 10.1080/15257779908041562. Nucleosides Nucleotides. 1999. PMID: 10432677

9

Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene.

Hong JS, Waud WR, Levasseur DN, Townes TM, Wen H, McPherson SA, Moore BA, Bebok Z, Allan PW, Secrist JA 3rd, Parker WB, Sorscher EJ. Hong JS, et al. Among authors: allan pw. Cancer Res. 2004 Sep 15;64(18):6610-5. doi: 10.1158/0008-5472.CAN-04-0012. Cancer Res. 2004. PMID: 15374975

10

6-Methylpurine derived sugar modified nucleosides: Synthesis and in vivo antitumor activity in D54 tumor expressing M64V-Escherichia coli purine nucleoside phosphorylase.

Hassan AEA, Abou-Elkhair RAI, Parker WB, Allan PW, Secrist JA 3rd. Hassan AEA, et al. Among authors: allan pw. Eur J Med Chem. 2016 Jan 27;108:616-622. doi: 10.1016/j.ejmech.2015.12.029. Epub 2015 Dec 17. Eur J Med Chem. 2016. PMID: 26724729

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