Motoi Y - Search Results

1

Intracellular TLR4/MD-2 in macrophages senses Gram-negative bacteria and induces a unique set of LPS-dependent genes.

Shibata T, Motoi Y, Tanimura N, Yamakawa N, Akashi-Takamura S, Miyake K. Shibata T, et al. Among authors: motoi y. Int Immunol. 2011 Aug;23(8):503-10. doi: 10.1093/intimm/dxr044. Epub 2011 Jun 28. Int Immunol. 2011. PMID: 21712422

2

PRAT4A-dependent expression of cell surface TLR5 on neutrophils, classical monocytes and dendritic cells.

Shibata T, Takemura N, Motoi Y, Goto Y, Karuppuchamy T, Izawa K, Li X, Akashi-Takamura S, Tanimura N, Kunisawa J, Kiyono H, Akira S, Kitamura T, Kitaura J, Uematsu S, Miyake K. Shibata T, et al. Among authors: motoi y. Int Immunol. 2012 Oct;24(10):613-23. doi: 10.1093/intimm/dxs068. Epub 2012 Jul 25. Int Immunol. 2012. PMID: 22836022

3

Essential role for Toll-like receptor 7 (TLR7)-unique cysteines in an intramolecular disulfide bond, proteolytic cleavage and RNA sensing.

Kanno A, Yamamoto C, Onji M, Fukui R, Saitoh S, Motoi Y, Shibata T, Matsumoto F, Muta T, Miyake K. Kanno A, et al. Among authors: motoi y. Int Immunol. 2013 Jul;25(7):413-22. doi: 10.1093/intimm/dxt007. Epub 2013 Feb 26. Int Immunol. 2013. PMID: 23446849

4

Lipopeptides are signaled by Toll-like receptor 1, 2 and 6 in endolysosomes.

Motoi Y, Shibata T, Takahashi K, Kanno A, Murakami Y, Li X, Kasahara T, Miyake K. Motoi Y, et al. Int Immunol. 2014 Oct;26(10):563-73. doi: 10.1093/intimm/dxu054. Epub 2014 May 24. Int Immunol. 2014. PMID: 24860120

5

Roles of the cleaved N-terminal TLR3 fragment and cell surface TLR3 in double-stranded RNA sensing.

Murakami Y, Fukui R, Motoi Y, Kanno A, Shibata T, Tanimura N, Saitoh S, Miyake K. Murakami Y, et al. Among authors: motoi y. J Immunol. 2014 Nov 15;193(10):5208-17. doi: 10.4049/jimmunol.1400386. Epub 2014 Oct 10. J Immunol. 2014. PMID: 25305318

6

Guanosine and its modified derivatives are endogenous ligands for TLR7.

Shibata T, Ohto U, Nomura S, Kibata K, Motoi Y, Zhang Y, Murakami Y, Fukui R, Ishimoto T, Sano S, Ito T, Shimizu T, Miyake K. Shibata T, et al. Among authors: motoi y. Int Immunol. 2016 May;28(5):211-22. doi: 10.1093/intimm/dxv062. Epub 2015 Oct 20. Int Immunol. 2016. PMID: 26489884 Free PMC article.

7

The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages.

Sato R, Reuter T, Hiranuma R, Shibata T, Fukui R, Motoi Y, Murakami Y, Tsukamoto H, Yamazaki S, Liu K, Saitoh SI, Latz E, Miyake K. Sato R, et al. Among authors: motoi y. Int Immunol. 2020 Nov 23;32(12):785-798. doi: 10.1093/intimm/dxaa055. Int Immunol. 2020. PMID: 32840578

8

The radioprotective 105/MD-1 complex links TLR2 and TLR4/MD-2 in antibody response to microbial membranes.

Nagai Y, Kobayashi T, Motoi Y, Ishiguro K, Akashi S, Saitoh S, Kusumoto Y, Kaisho T, Akira S, Matsumoto M, Takatsu K, Miyake K. Nagai Y, et al. Among authors: motoi y. J Immunol. 2005 Jun 1;174(11):7043-9. doi: 10.4049/jimmunol.174.11.7043. J Immunol. 2005. PMID: 15905547

9

An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing.

Onji M, Kanno A, Saitoh S, Fukui R, Motoi Y, Shibata T, Matsumoto F, Lamichhane A, Sato S, Kiyono H, Yamamoto K, Miyake K. Onji M, et al. Among authors: motoi y. Nat Commun. 2013;4:1949. doi: 10.1038/ncomms2949. Nat Commun. 2013. PMID: 23752491 Free article.

10

Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases.

Kanno A, Tanimura N, Ishizaki M, Ohko K, Motoi Y, Onji M, Fukui R, Shimozato T, Yamamoto K, Shibata T, Sano S, Sugahara-Tobinai A, Takai T, Ohto U, Shimizu T, Saitoh S, Miyake K. Kanno A, et al. Among authors: motoi y. Nat Commun. 2015 Feb 4;6:6119. doi: 10.1038/ncomms7119. Nat Commun. 2015. PMID: 25648980 Free article.

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