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Asc-dependent and independent mechanisms contribute to restriction of legionella pneumophila infection in murine macrophages.
Abdelaziz DH, Gavrilin MA, Akhter A, Caution K, Kotrange S, Khweek AA, Abdulrahman BA, Hassan ZA, El-Sharkawi FZ, Bedi SS, Ladner K, Gonzalez-Mejia ME, Doseff AI, Mostafa M, Kanneganti TD, Guttridge D, Marsh CB, Wewers MD, Amer AO. Abdelaziz DH, et al. Among authors: guttridge d. Front Microbiol. 2011 Feb 14;2:18. doi: 10.3389/fmicb.2011.00018. eCollection 2011. Front Microbiol. 2011. PMID: 21713115 Free PMC article.
Muscle inflammation is regulated by NF-κB from multiple cells to control distinct states of wasting in cancer cachexia.
Pryce BR, Oles A, Talbert EE, Romeo MJ, Vaena S, Sharma S, Spadafora V, Tolliver L, Mahvi DA, Morgan KA, Lancaster WP, Beal E, Koren N, Watts B, Overstreet M, Berto S, Subramanian S, Calisir K, Crawford A, Neelon B, Ostrowski MC, Zimmers TA, Tidball JG, Wang DJ, Guttridge DC. Pryce BR, et al. Among authors: guttridge dc. Cell Rep. 2024 Nov 26;43(11):114925. doi: 10.1016/j.celrep.2024.114925. Epub 2024 Oct 30. Cell Rep. 2024. PMID: 39475511 Free article.
The impact of inflammation and acute phase activation in cancer cachexia.
Robinson TP, Hamidi T, Counts B, Guttridge DC, Ostrowski MC, Zimmers TA, Koniaris LG. Robinson TP, et al. Among authors: guttridge dc. Front Immunol. 2023 Oct 31;14:1207746. doi: 10.3389/fimmu.2023.1207746. eCollection 2023. Front Immunol. 2023. PMID: 38022578 Free PMC article. Review.
Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance.
Gao X, Wu Y, Chick JM, Abbott A, Jiang B, Wang DJ, Comte-Walters S, Johnson RH, Oberholtzer N, Nishimura MI, Gygi SP, Mehta A, Guttridge DC, Ball L, Mehrotra S, Sicinski P, Yu XZ, Wang H. Gao X, et al. Among authors: guttridge dc. Cell Rep. 2023 Apr 25;42(4):112314. doi: 10.1016/j.celrep.2023.112314. Epub 2023 Mar 30. Cell Rep. 2023. PMID: 37000627 Free PMC article.
Cancer cachexia: involvement of an expanding macroenvironment.
Pryce BR, Wang DJ, Zimmers TA, Ostrowski MC, Guttridge DC. Pryce BR, et al. Among authors: guttridge dc. Cancer Cell. 2023 Mar 13;41(3):581-584. doi: 10.1016/j.ccell.2023.02.007. Epub 2023 Mar 2. Cancer Cell. 2023. PMID: 36868225 Free PMC article.
Redundant Signaling as the Predominant Mechanism for Resistance to Antibodies Targeting the Type-I Insulin-Like Growth Factor Receptor in Cells Derived from Childhood Sarcoma.
Shackleford TJ, Hariharan S, Vaseva AV, Alagoa K, Espinoza M, Bid HK, Li F, Zhong H, Phelps DA, Roberts RD, Cam H, London CA, Guttridge DC, Chen Y, Rao M, Shiio Y, Houghton PJ. Shackleford TJ, et al. Among authors: guttridge dc. Mol Cancer Ther. 2023 Apr 3;22(4):539-550. doi: 10.1158/1535-7163.MCT-20-0625. Mol Cancer Ther. 2023. PMID: 36696581 Free PMC article.
STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer.
Lefler JE, MarElia-Bennett CB, Thies KA, Hildreth BE 3rd, Sharma SM, Pitarresi JR, Han L, Everett C, Koivisto C, Cuitino MC, Timmers CD, O'Quinn E, Parrish M, Romeo MJ, Linke AJ, Hobbs GA, Leone G, Guttridge DC, Zimmers TA, Lesinski GB, Ostrowski MC. Lefler JE, et al. Among authors: guttridge dc. Life Sci Alliance. 2022 Jul 8;5(11):e202201460. doi: 10.26508/lsa.202201460. Print 2022 Nov. Life Sci Alliance. 2022. PMID: 35803738 Free PMC article.
150 results