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The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity.
Kool M, van Loo G, Waelput W, De Prijck S, Muskens F, Sze M, van Praet J, Branco-Madeira F, Janssens S, Reizis B, Elewaut D, Beyaert R, Hammad H, Lambrecht BN. Kool M, et al. Among authors: van loo g, van praet j. Immunity. 2011 Jul 22;35(1):82-96. doi: 10.1016/j.immuni.2011.05.013. Epub 2011 Jun 30. Immunity. 2011. PMID: 21723156 Free article.
The autoinflammation-associated NLRC4V341A mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice.
Eeckhout E, Asaoka T, Van Gorp H, Demon D, Girard-Guyonvarc'h C, Andries V, Vereecke L, Gabay C, Lamkanfi M, van Loo G, Wullaert A. Eeckhout E, et al. Among authors: van loo g. Front Immunol. 2023 Nov 28;14:1272639. doi: 10.3389/fimmu.2023.1272639. eCollection 2023. Front Immunol. 2023. PMID: 38090573 Free PMC article.
Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease.
Srinivasan S, Kancheva D, De Ren S, Saito T, Jans M, Boone F, Vandendriessche C, Paesmans I, Maurin H, Vandenbroucke RE, Hoste E, Voet S, Scheyltjens I, Pavie B, Lippens S, Schwabenland M, Prinz M, Saido T, Bottelbergs A, Movahedi K, Lamkanfi M, van Loo G. Srinivasan S, et al. Among authors: van loo g. Front Immunol. 2024 Jan 29;15:1323409. doi: 10.3389/fimmu.2024.1323409. eCollection 2024. Front Immunol. 2024. PMID: 38352874 Free PMC article.
Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression.
Van San E, Debruyne AC, Veeckmans G, Tyurina YY, Tyurin VA, Zheng H, Choi SM, Augustyns K, van Loo G, Michalke B, Venkataramani V, Toyokuni S, Bayir H, Vandenabeele P, Hassannia B, Vanden Berghe T. Van San E, et al. Among authors: van loo g. Cell Death Differ. 2023 Sep;30(9):2092-2103. doi: 10.1038/s41418-023-01195-0. Epub 2023 Aug 4. Cell Death Differ. 2023. PMID: 37542104 Free PMC article.
Glycyrrhizin-Based Hydrogels Accelerate Wound Healing of Normoglycemic and Diabetic Mouse Skin.
Mees MA, Boone F, Bouwen T, Vanaerschot F, Titeca C, Vikkula HK, Catrysse L, Vananroye A, Koos E, Alexandris S, Rosenfeldt S, Eyley S, Koetz J, van Loo G, Thielemans W, Hoste E. Mees MA, et al. Among authors: van loo g. Pharmaceutics. 2022 Dec 21;15(1):27. doi: 10.3390/pharmaceutics15010027. Pharmaceutics. 2022. PMID: 36678656 Free PMC article.
NLRP3 inflammasome activation and pyroptosis are dispensable for tau pathology.
Paesmans I, Van Kolen K, Vandermeeren M, Shih PY, Wuyts D, Boone F, Garcia Sanchez S, Grauwen K, Van Hauwermeiren F, Van Opdenbosch N, Lamkanfi M, van Loo G, Bottelbergs A. Paesmans I, et al. Among authors: van loo g. Front Aging Neurosci. 2024 Sep 24;16:1459134. doi: 10.3389/fnagi.2024.1459134. eCollection 2024. Front Aging Neurosci. 2024. PMID: 39381137 Free PMC article.
Death by TNF: a road to inflammation.
van Loo G, Bertrand MJM. van Loo G, et al. Nat Rev Immunol. 2023 May;23(5):289-303. doi: 10.1038/s41577-022-00792-3. Epub 2022 Nov 15. Nat Rev Immunol. 2023. PMID: 36380021 Free PMC article. Review.
Lithium sensitizes tumor cells in an NF-kappa B-independent way to caspase activation and apoptosis induced by tumor necrosis factor (TNF). Evidence for a role of the TNF receptor-associated death domain protein.
Schotte P, Van Loo G, Carpentier I, Vandenabeele P, Beyaert R. Schotte P, et al. Among authors: van loo g. J Biol Chem. 2001 Jul 13;276(28):25939-45. doi: 10.1074/jbc.M104014200. Epub 2001 May 7. J Biol Chem. 2001. PMID: 11342564 Free article.
162 results