Pollack SJ - Search Results

1

A comparative study of fragment screening methods on the p38α kinase: new methods, new insights.

Pollack SJ, Beyer KS, Lock C, Müller I, Sheppard D, Lipkin M, Hardick D, Blurton P, Leonard PM, Hubbard PA, Todd D, Richardson CM, Ahrens T, Baader M, Hafenbradl DO, Hilyard K, Bürli RW. Pollack SJ, et al. J Comput Aided Mol Des. 2011 Jul;25(7):677-87. doi: 10.1007/s10822-011-9454-9. Epub 2011 Jul 6. J Comput Aided Mol Des. 2011. PMID: 21732248 Free PMC article.

2

Substituting c-Jun N-terminal kinase-3 (JNK3) ATP-binding site amino acid residues with their p38 counterparts affects binding of JNK- and p38-selective inhibitors.

Fricker M, Lograsso P, Ellis S, Wilkie N, Hunt P, Pollack SJ. Fricker M, et al. Among authors: pollack sj. Arch Biochem Biophys. 2005 Jun 15;438(2):195-205. doi: 10.1016/j.abb.2005.04.013. Arch Biochem Biophys. 2005. PMID: 15907786

3

The non-peptidyl fungal metabolite L-783,281 activates TRK neurotrophin receptors.

Wilkie N, Wingrove PB, Bilsland JG, Young L, Harper SJ, Hefti F, Ellis S, Pollack SJ. Wilkie N, et al. Among authors: pollack sj. J Neurochem. 2001 Sep;78(5):1135-45. doi: 10.1046/j.1471-4159.2001.00504.x. J Neurochem. 2001. PMID: 11553687 Free article.

4

The staurosporine-like compound L-753,000 (NB-506) potentiates the neurotrophic effects of neurotrophin-3 by acting selectively at the TrkA receptor.

Pollack S, Young L, Bilsland J, Wilkie N, Ellis S, Hefti F, Broughton H, Harper S. Pollack S, et al. Mol Pharmacol. 1999 Jul;56(1):185-95. doi: 10.1124/mol.56.1.185. Mol Pharmacol. 1999. PMID: 10385700

5

Probing the role of metal ions in the mechanism of inositol monophosphatase by site-directed mutagenesis.

Pollack SJ, Knowles MR, Atack JR, Broughton HB, Ragan CI, Osborne S, McAllister G. Pollack SJ, et al. Eur J Biochem. 1993 Oct 1;217(1):281-7. doi: 10.1111/j.1432-1033.1993.tb18244.x. Eur J Biochem. 1993. PMID: 8223565 Free article.

6

Growth factors regulate the survival and fate of cells derived from human neurospheres.

Caldwell MA, He X, Wilkie N, Pollack S, Marshall G, Wafford KA, Svendsen CN. Caldwell MA, et al. Nat Biotechnol. 2001 May;19(5):475-9. doi: 10.1038/88158. Nat Biotechnol. 2001. PMID: 11329020

7

Catalytic site-directed gamma-secretase complex inhibitors do not discriminate pharmacologically between Notch S3 and beta-APP cleavages.

Lewis HD, Pérez Revuelta BI, Nadin A, Neduvelil JG, Harrison T, Pollack SJ, Shearman MS. Lewis HD, et al. Among authors: pollack sj. Biochemistry. 2003 Jun 24;42(24):7580-6. doi: 10.1021/bi034310g. Biochemistry. 2003. PMID: 12809514

8

Structural analysis of inositol monophosphatase complexes with substrates.

Bone R, Frank L, Springer JP, Pollack SJ, Osborne SA, Atack JR, Knowles MR, McAllister G, Ragan CI, Broughton HB, et al. Bone R, et al. Among authors: pollack sj. Biochemistry. 1994 Aug 16;33(32):9460-7. doi: 10.1021/bi00198a011. Biochemistry. 1994. PMID: 8068620

9

Mechanism of inositol monophosphatase, the putative target of lithium therapy.

Pollack SJ, Atack JR, Knowles MR, McAllister G, Ragan CI, Baker R, Fletcher SR, Iversen LL, Broughton HB. Pollack SJ, et al. Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):5766-70. doi: 10.1073/pnas.91.13.5766. Proc Natl Acad Sci U S A. 1994. PMID: 8016062 Free PMC article.

10

Secretase inhibitors for Alzheimer's disease: challenges of a promiscuous protease.

Pollack SJ, Lewis H. Pollack SJ, et al. Curr Opin Investig Drugs. 2005 Jan;6(1):35-47. Curr Opin Investig Drugs. 2005. PMID: 15675602 Review.

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