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Phase I clinical and pharmacological study of merbarone.
Dimaggio JJ, Warrell RP Jr, Muindi J, Stevens YW, Lee SJ, Lowenthal DA, Haines I, Walsh TD, Baltzer L, Yaldaei S, et al. Dimaggio JJ, et al. Among authors: muindi j. Cancer Res. 1990 Feb 15;50(4):1151-5. Cancer Res. 1990. PMID: 2297763
Lipid hydroperoxides greatly increase the rate of oxidative catabolism of all-trans-retinoic acid by human cell culture microsomes genetically enriched in specified cytochrome P-450 isoforms.
Muindi JF, Young CW. Muindi JF, et al. Cancer Res. 1993 Mar 15;53(6):1226-9. Cancer Res. 1993. PMID: 8383004
Cytochrome P-450 enzymes have been implicated in the oxidative catabolism of all-trans-retinoic acid (RA), a process that is accelerated by exposure to RA in cultured cells and rodents, and also in patients receiving RA as treatment for cancer (J.F.R. Muindi et al., …
Cytochrome P-450 enzymes have been implicated in the oxidative catabolism of all-trans-retinoic acid (RA), a process that is accelerated by …
61 results