Elefteriou F - Search Results

1

Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I.

Wang W, Nyman JS, Ono K, Stevenson DA, Yang X, Elefteriou F. Wang W, et al. Among authors: elefteriou f. Hum Mol Genet. 2011 Oct 15;20(20):3910-24. doi: 10.1093/hmg/ddr310. Epub 2011 Jul 14. Hum Mol Genet. 2011. PMID: 21757497 Free PMC article.

2

The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.

Ono K, Karolak MR, Ndong Jde L, Wang W, Yang X, Elefteriou F. Ono K, et al. Among authors: elefteriou f. Hum Mol Genet. 2013 Aug 1;22(15):3048-62. doi: 10.1093/hmg/ddt162. Epub 2013 Apr 9. Hum Mol Genet. 2013. PMID: 23571107 Free PMC article.

3

Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.

de la Croix Ndong J, Makowski AJ, Uppuganti S, Vignaux G, Ono K, Perrien DS, Joubert S, Baglio SR, Granchi D, Stevenson DA, Rios JJ, Nyman JS, Elefteriou F. de la Croix Ndong J, et al. Among authors: elefteriou f. Nat Med. 2014 Aug;20(8):904-10. doi: 10.1038/nm.3583. Epub 2014 Jul 6. Nat Med. 2014. PMID: 24997609 Free PMC article.

4

FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation.

Karolak MR, Yang X, Elefteriou F. Karolak MR, et al. Among authors: elefteriou f. Hum Mol Genet. 2015 May 1;24(9):2552-64. doi: 10.1093/hmg/ddv019. Epub 2015 Jan 23. Hum Mol Genet. 2015. PMID: 25616962 Free PMC article.

5

Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.

Wang W, Nyman JS, Moss HE, Gutierrez G, Mundy GR, Yang X, Elefteriou F. Wang W, et al. Among authors: elefteriou f. J Bone Miner Res. 2010 Jul;25(7):1658-67. doi: 10.1002/jbmr.42. J Bone Miner Res. 2010. PMID: 20200958 Free PMC article.

6

β2-Adrenergic receptor signaling in osteoblasts contributes to the catabolic effect of glucocorticoids on bone.

Ma Y, Nyman JS, Tao H, Moss HH, Yang X, Elefteriou F. Ma Y, et al. Among authors: elefteriou f. Endocrinology. 2011 Apr;152(4):1412-22. doi: 10.1210/en.2010-0881. Epub 2011 Jan 25. Endocrinology. 2011. PMID: 21266510 Free PMC article.

7

Genetic mouse models for bone studies--strengths and limitations.

Elefteriou F, Yang X. Elefteriou F, et al. Bone. 2011 Dec;49(6):1242-54. doi: 10.1016/j.bone.2011.08.021. Epub 2011 Aug 31. Bone. 2011. PMID: 21907838 Free PMC article. Review.

8

Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling.

Edwards JR, Perrien DS, Fleming N, Nyman JS, Ono K, Connelly L, Moore MM, Lwin ST, Yull FE, Mundy GR, Elefteriou F. Edwards JR, et al. Among authors: elefteriou f. J Bone Miner Res. 2013 Apr;28(4):960-9. doi: 10.1002/jbmr.1824. J Bone Miner Res. 2013. PMID: 23172686 Free article.

9

Extracellular norepinephrine clearance by the norepinephrine transporter is required for skeletal homeostasis.

Ma Y, Krueger JJ, Redmon SN, Uppuganti S, Nyman JS, Hahn MK, Elefteriou F. Ma Y, et al. Among authors: elefteriou f. J Biol Chem. 2013 Oct 18;288(42):30105-30113. doi: 10.1074/jbc.M113.481309. Epub 2013 Sep 4. J Biol Chem. 2013. PMID: 24005671 Free PMC article.

10

Multiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1.

Kühnisch J, Seto J, Lange C, Schrof S, Stumpp S, Kobus K, Grohmann J, Kossler N, Varga P, Osswald M, Emmerich D, Tinschert S, Thielemann F, Duda G, Seifert W, El Khassawna T, Stevenson DA, Elefteriou F, Kornak U, Raum K, Fratzl P, Mundlos S, Kolanczyk M. Kühnisch J, et al. Among authors: elefteriou f. PLoS One. 2014 Jan 21;9(1):e86115. doi: 10.1371/journal.pone.0086115. eCollection 2014. PLoS One. 2014. PMID: 24465906 Free PMC article.

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