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TORCing up the importance of calcium signaling.
Lavin PJ, Winn MP. Lavin PJ, et al. J Am Soc Nephrol. 2011 Aug;22(8):1391-3. doi: 10.1681/ASN.2011060595. Epub 2011 Jul 14. J Am Soc Nephrol. 2011. PMID: 21757772 No abstract available.
A new locus for familial FSGS on chromosome 2p.
Gbadegesin R, Lavin P, Janssens L, Bartkowiak B, Homstad A, Wu G, Bowling B, Eckel J, Potocky C, Abbott D, Conlon P, Scott WK, Howell D, Hauser E, Winn MP. Gbadegesin R, et al. J Am Soc Nephrol. 2010 Aug;21(8):1390-7. doi: 10.1681/ASN.2009101046. Epub 2010 Jul 8. J Am Soc Nephrol. 2010. PMID: 20616172 Free PMC article.
TNXB mutations can cause vesicoureteral reflux.
Gbadegesin RA, Brophy PD, Adeyemo A, Hall G, Gupta IR, Hains D, Bartkowiak B, Rabinovich CE, Chandrasekharappa S, Homstad A, Westreich K, Wu G, Liu Y, Holanda D, Clarke J, Lavin P, Selim A, Miller S, Wiener JS, Ross SS, Foreman J, Rotimi C, Winn MP. Gbadegesin RA, et al. J Am Soc Nephrol. 2013 Jul;24(8):1313-22. doi: 10.1681/ASN.2012121148. Epub 2013 Apr 25. J Am Soc Nephrol. 2013. PMID: 23620400 Free PMC article.
Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS.
Gbadegesin RA, Hall G, Adeyemo A, Hanke N, Tossidou I, Burchette J, Wu G, Homstad A, Sparks MA, Gomez J, Jiang R, Alonso A, Lavin P, Conlon P, Korstanje R, Stander MC, Shamsan G, Barua M, Spurney R, Singhal PC, Kopp JB, Haller H, Howell D, Pollak MR, Shaw AS, Schiffer M, Winn MP. Gbadegesin RA, et al. J Am Soc Nephrol. 2014 Sep;25(9):1991-2002. doi: 10.1681/ASN.2013090976. Epub 2014 Mar 27. J Am Soc Nephrol. 2014. PMID: 24676636 Free PMC article.
A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS.
Hall G, Gbadegesin RA, Lavin P, Wu G, Liu Y, Oh EC, Wang L, Spurney RF, Eckel J, Lindsey T, Homstad A, Malone AF, Phelan PJ, Shaw A, Howell DN, Conlon PJ, Katsanis N, Winn MP. Hall G, et al. Among authors: lavin p. J Am Soc Nephrol. 2015 Apr;26(4):831-43. doi: 10.1681/ASN.2013101053. Epub 2014 Aug 21. J Am Soc Nephrol. 2015. PMID: 25145932 Free PMC article.
TRPC6 enhances angiotensin II-induced albuminuria.
Eckel J, Lavin PJ, Finch EA, Mukerji N, Burch J, Gbadegesin R, Wu G, Bowling B, Byrd A, Hall G, Sparks M, Zhang ZS, Homstad A, Barisoni L, Birbaumer L, Rosenberg P, Winn MP. Eckel J, et al. Among authors: lavin pj. J Am Soc Nephrol. 2011 Mar;22(3):526-35. doi: 10.1681/ASN.2010050522. Epub 2011 Jan 21. J Am Soc Nephrol. 2011. PMID: 21258036 Free PMC article.
A hybrid CFHR3-1 gene causes familial C3 glomerulopathy.
Malik TH, Lavin PJ, Goicoechea de Jorge E, Vernon KA, Rose KL, Patel MP, de Leeuw M, Neary JJ, Conlon PJ, Winn MP, Pickering MC. Malik TH, et al. Among authors: lavin pj. J Am Soc Nephrol. 2012 Jul;23(7):1155-60. doi: 10.1681/ASN.2012020166. Epub 2012 May 24. J Am Soc Nephrol. 2012. PMID: 22626820 Free PMC article.
Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity.
Hall G, Rowell J, Farinelli F, Gbadegesin RA, Lavin P, Wu G, Homstad A, Malone A, Lindsey T, Jiang R, Spurney R, Tomaselli GF, Kass DA, Winn MP. Hall G, et al. Am J Physiol Renal Physiol. 2014 Jun 15;306(12):F1442-50. doi: 10.1152/ajprenal.00212.2013. Epub 2014 Apr 16. Am J Physiol Renal Physiol. 2014. PMID: 24740790 Free PMC article.
Therapeutic targets in focal and segmental glomerulosclerosis.
Lavin PJ, Gbadegesin R, Damodaran TV, Winn MP. Lavin PJ, et al. Curr Opin Nephrol Hypertens. 2008 Jul;17(4):386-92. doi: 10.1097/MNH.0b013e32830464f4. Curr Opin Nephrol Hypertens. 2008. PMID: 18660675 Free PMC article. Review.
77 results