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The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans.
Weissglas-Volkov D, Calkin AC, Tusie-Luna T, Sinsheimer JS, Zelcer N, Riba L, Tino AM, Ordoñez-Sánchez ML, Cruz-Bautista I, Aguilar-Salinas CA, Tontonoz P, Pajukanta P. Weissglas-Volkov D, et al. Among authors: zelcer n. J Clin Invest. 2011 Aug;121(8):3062-71. doi: 10.1172/JCI45504. Epub 2011 Jul 18. J Clin Invest. 2011. PMID: 21765216 Free PMC article.
Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages.
van Wouw SAE, van den Berg M, El Ouraoui M, Meurs A, Kingma J, Ottenhoff R, Loix M, Hoeksema MA, Prange K, Pasterkamp G, Hendriks JJA, Bogie JFJ, van Klinken JB, Vaz FM, Jongejan A, de Winther MPJ, Zelcer N. van Wouw SAE, et al. Among authors: zelcer n. J Lipid Res. 2023 Feb;64(2):100325. doi: 10.1016/j.jlr.2022.100325. Epub 2022 Dec 31. J Lipid Res. 2023. PMID: 36592658 Free PMC article.
DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability.
Willemsen L, Prange KHM, Neele AE, van Roomen CPAA, Gijbels M, Griffith GR, Toom MD, Beckers L, Siebeler R, Spann NJ, Chen HJ, Bosmans LA, Gorbatenko A, van Wouw S, Zelcer N, Jacobs H, van Leeuwen F, de Winther MPJ. Willemsen L, et al. Among authors: zelcer n. Cell Rep. 2022 Nov 22;41(8):111703. doi: 10.1016/j.celrep.2022.111703. Cell Rep. 2022. PMID: 36417856 Free article.
Hyperlipidaemia elicits an atypical, T helper 1-like CD4+ T-cell response: a key role for very low-density lipoprotein.
van Os BW, Vos WG, Bosmans LA, van Tiel CM, Lith SC, den Toom MS, Beckers L, Levels JHM, van Wouw SAE, Zelcer N, Zaal EA, Berkers CR, van der Lest CHA, Helms JB, Weber C, Atzler D, de Winther MPJ, Baardman J, Lutgens E. van Os BW, et al. Among authors: zelcer n. Eur Heart J Open. 2023 Mar 3;3(2):oead013. doi: 10.1093/ehjopen/oead013. eCollection 2023 Mar. Eur Heart J Open. 2023. PMID: 36969380 Free PMC article.
Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2.
Vacondio D, Nogueira Pinto H, Coenen L, Mulder IA, Fontijn R, van Het Hof B, Fung WK, Jongejan A, Kooij G, Zelcer N, Rozemuller AJ, de Vries HE, de Wit NM. Vacondio D, et al. Among authors: zelcer n. Cell Death Dis. 2023 Nov 28;14(11):781. doi: 10.1038/s41419-023-06316-8. Cell Death Dis. 2023. PMID: 38016947 Free PMC article.
92 results