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A carrier protein strategy yields the structure of dalbavancin.
Economou NJ, Nahoum V, Weeks SD, Grasty KC, Zentner IJ, Townsend TM, Bhuiya MW, Cocklin S, Loll PJ. Economou NJ, et al. J Am Chem Soc. 2012 Mar 14;134(10):4637-45. doi: 10.1021/ja208755j. Epub 2012 Mar 1. J Am Chem Soc. 2012. PMID: 22352468 Free PMC article.
A unitary anesthetic binding site at high resolution.
Vedula LS, Brannigan G, Economou NJ, Xi J, Hall MA, Liu R, Rossi MJ, Dailey WP, Grasty KC, Klein ML, Eckenhoff RG, Loll PJ. Vedula LS, et al. Among authors: economou nj. J Biol Chem. 2009 Sep 4;284(36):24176-84. doi: 10.1074/jbc.M109.017814. Epub 2009 Jul 15. J Biol Chem. 2009. PMID: 19605349 Free PMC article.
Enzymatic basis of "hybridity" in thiomarinol biosynthesis.
Dunn ZD, Wever WJ, Economou NJ, Bowers AA, Li B. Dunn ZD, et al. Among authors: economou nj. Angew Chem Int Ed Engl. 2015 Apr 20;54(17):5137-41. doi: 10.1002/anie.201411667. Epub 2015 Feb 26. Angew Chem Int Ed Engl. 2015. PMID: 25726835 Free PMC article.
14 results