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A low-frequency haplotype spanning SLX4/FANCP constitutes a new risk locus for early-onset breast cancer (<60 years) and is associated with reduced DNA repair capacity.
Surowy H, Varga D, Burwinkel B, Marmé F, Sohn C, Luedeke M, Rinckleb A, Maier C, Deissler H, Volcic M, Wiesmüller L, Hasenburg A, Klar M, Hoegel J, Vogel W. Surowy H, et al. Among authors: volcic m. Int J Cancer. 2018 Feb 15;142(4):757-768. doi: 10.1002/ijc.31105. Epub 2017 Oct 30. Int J Cancer. 2018. PMID: 29044504
Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1.
Volcic M, Sparrer KMJ, Koepke L, Hotter D, Sauter D, Stürzel CM, Scherer M, Stamminger T, Hofmann TG, Arhel NJ, Wiesmüller L, Kirchhoff F. Volcic M, et al. Nat Microbiol. 2020 Oct;5(10):1247-1261. doi: 10.1038/s41564-020-0753-6. Epub 2020 Jul 20. Nat Microbiol. 2020. PMID: 32690953 Free PMC article.
Small but Highly Versatile: The Viral Accessory Protein Vpu.
Volcic M, Wiesmüller L, Kirchhoff F. Volcic M, et al. Annu Rev Virol. 2023 Sep 29;10(1):243-259. doi: 10.1146/annurev-virology-111821-100816. Epub 2023 Jul 5. Annu Rev Virol. 2023. PMID: 37406340 Free article. Review.
Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.
Bosso M, Prelli Bozzo C, Hotter D, Volcic M, Stürzel CM, Rammelt A, Ni Y, Urban S, Becker M, Schelhaas M, Wittmann S, Christensen MH, Schmidt FI, Gramberg T, Sparrer KMJ, Sauter D, Kirchhoff F. Bosso M, et al. Among authors: volcic m. PLoS Pathog. 2020 Aug 6;16(8):e1008752. doi: 10.1371/journal.ppat.1008752. eCollection 2020 Aug. PLoS Pathog. 2020. PMID: 32760121 Free PMC article.
22 results