Moore DT - Search Results

1

Computational design of a β-peptide that targets transmembrane helices.

Shandler SJ, Korendovych IV, Moore DT, Smith-Dupont KB, Streu CN, Litvinov RI, Billings PC, Gai F, Bennett JS, DeGrado WF. Shandler SJ, et al. Among authors: moore dt. J Am Chem Soc. 2011 Aug 17;133(32):12378-81. doi: 10.1021/ja204215f. Epub 2011 Jul 22. J Am Chem Soc. 2011. PMID: 21780757 Free PMC article.

2

Activation of platelet alphaIIbbeta3 by an exogenous peptide corresponding to the transmembrane domain of alphaIIb.

Yin H, Litvinov RI, Vilaire G, Zhu H, Li W, Caputo GA, Moore DT, Lear JD, Weisel JW, Degrado WF, Bennett JS. Yin H, et al. Among authors: moore dt. J Biol Chem. 2006 Dec 1;281(48):36732-41. doi: 10.1074/jbc.M605877200. Epub 2006 Oct 10. J Biol Chem. 2006. PMID: 17032655 Free article.

3

Arylamide derivatives as allosteric inhibitors of the integrin alpha2beta1/type I collagen interaction.

Yin H, Gerlach LO, Miller MW, Moore DT, Liu D, Vilaire G, Bennett JS, DeGrado WF. Yin H, et al. Among authors: moore dt. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3380-2. doi: 10.1016/j.bmcl.2006.04.037. Epub 2006 May 5. Bioorg Med Chem Lett. 2006. PMID: 16678410

4

Protein-protein interactions in the membrane: sequence, structural, and biological motifs.

Moore DT, Berger BW, DeGrado WF. Moore DT, et al. Structure. 2008 Jul;16(7):991-1001. doi: 10.1016/j.str.2008.05.007. Structure. 2008. PMID: 18611372 Free PMC article. Review.

5

NMR analysis of the alphaIIb beta3 cytoplasmic interaction suggests a mechanism for integrin regulation.

Metcalf DG, Moore DT, Wu Y, Kielec JM, Molnar K, Valentine KG, Wand AJ, Bennett JS, DeGrado WF. Metcalf DG, et al. Among authors: moore dt. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22481-6. doi: 10.1073/pnas.1015545107. Epub 2010 Dec 14. Proc Natl Acad Sci U S A. 2010. PMID: 21156831 Free PMC article.

6

Transmembrane communication: general principles and lessons from the structure and function of the M2 proton channel, K⁺ channels, and integrin receptors.

Grigoryan G, Moore DT, DeGrado WF. Grigoryan G, et al. Among authors: moore dt. Annu Rev Biochem. 2011;80:211-37. doi: 10.1146/annurev-biochem-091008-152423. Annu Rev Biochem. 2011. PMID: 21548783 Free PMC article. Review.

7

Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment.

Moore DT, Nygren P, Jo H, Boesze-Battaglia K, Bennett JS, DeGrado WF. Moore DT, et al. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):793-8. doi: 10.1073/pnas.1117220108. Epub 2011 Dec 30. Proc Natl Acad Sci U S A. 2012. PMID: 22210111 Free PMC article.

8

The Tyrosine Kinase c-Src Specifically Binds to the Active Integrin αIIbβ3 to Initiate Outside-in Signaling in Platelets.

Wu Y, Span LM, Nygren P, Zhu H, Moore DT, Cheng H, Roder H, DeGrado WF, Bennett JS. Wu Y, et al. Among authors: moore dt. J Biol Chem. 2015 Jun 19;290(25):15825-15834. doi: 10.1074/jbc.M115.648428. Epub 2015 May 6. J Biol Chem. 2015. PMID: 25947380 Free PMC article.

9

Directly Activating the Integrin αIIbβ3 Initiates Outside-In Signaling by Causing αIIbβ3 Clustering.

Fong KP, Zhu H, Span LM, Moore DT, Yoon K, Tamura R, Yin H, DeGrado WF, Bennett JS. Fong KP, et al. Among authors: moore dt. J Biol Chem. 2016 May 27;291(22):11706-16. doi: 10.1074/jbc.M116.716613. Epub 2016 Apr 7. J Biol Chem. 2016. PMID: 27056329 Free PMC article.

10

Regulation of platelet beta 3 integrins.

Bennett JS, Moore DT. Bennett JS, et al. Among authors: moore dt. Haematologica. 2010 Jul;95(7):1049-51. doi: 10.3324/haematol.2010.024893. Haematologica. 2010. PMID: 20595101 Free PMC article. Review. No abstract available.

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