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Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells.
Svensson KJ, Kucharzewska P, Christianson HC, Sköld S, Löfstedt T, Johansson MC, Mörgelin M, Bengzon J, Ruf W, Belting M. Svensson KJ, et al. Among authors: lofstedt t. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13147-52. doi: 10.1073/pnas.1104261108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788507 Free PMC article.
Stem cell factor induces HIF-1alpha at normoxia in hematopoietic cells.
Pedersen M, Löfstedt T, Sun J, Holmquist-Mengelbier L, Påhlman S, Rönnstrand L. Pedersen M, et al. Among authors: lofstedt t. Biochem Biophys Res Commun. 2008 Dec 5;377(1):98-103. doi: 10.1016/j.bbrc.2008.09.102. Epub 2008 Oct 1. Biochem Biophys Res Commun. 2008. PMID: 18834862
Hypoxia inducible factor-2alpha in cancer.
Löfstedt T, Fredlund E, Holmquist-Mengelbier L, Pietras A, Ovenberger M, Poellinger L, Påhlman S. Löfstedt T, et al. Cell Cycle. 2007 Apr 15;6(8):919-26. doi: 10.4161/cc.6.8.4133. Epub 2007 Apr 13. Cell Cycle. 2007. PMID: 17404509 Review.
Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype.
Holmquist-Mengelbier L, Fredlund E, Löfstedt T, Noguera R, Navarro S, Nilsson H, Pietras A, Vallon-Christersson J, Borg A, Gradin K, Poellinger L, Påhlman S. Holmquist-Mengelbier L, et al. Among authors: lofstedt t. Cancer Cell. 2006 Nov;10(5):413-23. doi: 10.1016/j.ccr.2006.08.026. Cancer Cell. 2006. PMID: 17097563 Free article.
A human ICAM-1 antibody isolated by a function-first approach has potent macrophage-dependent antimyeloma activity in vivo.
Veitonmäki N, Hansson M, Zhan F, Sundberg A, Löfstedt T, Ljungars A, Li ZC, Martinsson-Niskanen T, Zeng M, Yang Y, Danielsson L, Kovacek M, Lundqvist A, Mårtensson L, Teige I, Tricot G, Frendéus B. Veitonmäki N, et al. Among authors: lofstedt t. Cancer Cell. 2013 Apr 15;23(4):502-15. doi: 10.1016/j.ccr.2013.02.026. Cancer Cell. 2013. PMID: 23597564 Free article.
40 results