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Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1 diabetes.
Marzo N, Mora C, Fabregat ME, Martín J, Usac EF, Franco C, Barbacid M, Gomis R. Marzo N, et al. Among authors: gomis r. Diabetologia. 2004 Apr;47(4):686-94. doi: 10.1007/s00125-004-1372-0. Diabetologia. 2004. PMID: 15298346
BACE2 plays a role in the insulin receptor trafficking in pancreatic ß-cells.
Casas S, Casini P, Piquer S, Altirriba J, Soty M, Cadavez L, Gomis R, Novials A. Casas S, et al. Among authors: gomis r. Am J Physiol Endocrinol Metab. 2010 Dec;299(6):E1087-95. doi: 10.1152/ajpendo.00420.2010. Epub 2010 Oct 13. Am J Physiol Endocrinol Metab. 2010. PMID: 20943756 Free article.
471 results