Pasternak A - Search Results

1

Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2'-C-piperazino-UNA monomer.

Jensen TB, Henriksen JR, Rasmussen BE, Rasmussen LM, Andresen TL, Wengel J, Pasternak A. Jensen TB, et al. Among authors: pasternak a. Bioorg Med Chem. 2011 Aug 15;19(16):4739-45. doi: 10.1016/j.bmc.2011.06.087. Epub 2011 Jul 7. Bioorg Med Chem. 2011. PMID: 21795054

2

UNA (unlocked nucleic acid): a flexible RNA mimic that allows engineering of nucleic acid duplex stability.

Langkjaer N, Pasternak A, Wengel J. Langkjaer N, et al. Among authors: pasternak a. Bioorg Med Chem. 2009 Aug 1;17(15):5420-5. doi: 10.1016/j.bmc.2009.06.045. Epub 2009 Jun 27. Bioorg Med Chem. 2009. PMID: 19604699

3

Thermodynamics of RNA duplexes modified with unlocked nucleic acid nucleotides.

Pasternak A, Wengel J. Pasternak A, et al. Nucleic Acids Res. 2010 Oct;38(19):6697-706. doi: 10.1093/nar/gkq561. Epub 2010 Jun 18. Nucleic Acids Res. 2010. PMID: 20562222 Free PMC article.

4

Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer.

Pasternak A, Hernandez FJ, Rasmussen LM, Vester B, Wengel J. Pasternak A, et al. Nucleic Acids Res. 2011 Feb;39(3):1155-64. doi: 10.1093/nar/gkq823. Epub 2010 Sep 24. Nucleic Acids Res. 2011. PMID: 20870750 Free PMC article.

5

Modulation of i-motif thermodynamic stability by the introduction of UNA (unlocked nucleic acid) monomers.

Pasternak A, Wengel J. Pasternak A, et al. Bioorg Med Chem Lett. 2011 Jan 15;21(2):752-5. doi: 10.1016/j.bmcl.2010.11.106. Epub 2010 Nov 26. Bioorg Med Chem Lett. 2011. PMID: 21185179

6

Unlocked nucleic acid--an RNA modification with broad potential.

Pasternak A, Wengel J. Pasternak A, et al. Org Biomol Chem. 2011 May 21;9(10):3591-7. doi: 10.1039/c0ob01085e. Epub 2011 Mar 23. Org Biomol Chem. 2011. PMID: 21431171 Review.

7

Synthesis and structural characterization of 2'-fluoro-α-L-RNA-modified oligonucleotides.

Bundgaard Jensen T, Pasternak A, Stahl Madsen A, Petersen M, Wengel J. Bundgaard Jensen T, et al. Among authors: pasternak a. Chembiochem. 2011 Aug 16;12(12):1904-11. doi: 10.1002/cbic.201100161. Epub 2011 Jul 4. Chembiochem. 2011. PMID: 21728225 Free article.

8

Photoligation of self-assembled DNA constructs containing anthracene-functionalized 2'-amino-LNA monomers.

Pasternak K, Pasternak A, Gupta P, Veedu RN, Wengel J. Pasternak K, et al. Among authors: pasternak a. Bioorg Med Chem. 2011 Dec 15;19(24):7407-15. doi: 10.1016/j.bmc.2011.10.052. Epub 2011 Oct 20. Bioorg Med Chem. 2011. PMID: 22079866

9

Pyrene-modified unlocked nucleic acids: synthesis, thermodynamic studies, and fluorescent properties.

Karlsen KK, Pasternak A, Jensen TB, Wengel J. Karlsen KK, et al. Among authors: pasternak a. Chembiochem. 2012 Mar 5;13(4):590-601. doi: 10.1002/cbic.201100689. Epub 2012 Feb 7. Chembiochem. 2012. PMID: 22315188 Free article.

10

Unlocked nucleic acids: implications of increased conformational flexibility for RNA/DNA triplex formation.

Kotkowiak W, Kotkowiak M, Kierzek R, Pasternak A. Kotkowiak W, et al. Among authors: pasternak a. Biochem J. 2014 Dec 1;464(2):203-11. doi: 10.1042/BJ20141023. Biochem J. 2014. PMID: 25226286

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