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Combination treatment with fulvestrant and various cytotoxic agents (doxorubicin, paclitaxel, docetaxel, vinorelbine, and 5-fluorouracil) has a synergistic effect in estrogen receptor-positive breast cancer.
Ikeda H, Taira N, Nogami T, Shien K, Okada M, Shien T, Doihara H, Miyoshi S. Ikeda H, et al. Among authors: nogami t. Cancer Sci. 2011 Nov;102(11):2038-42. doi: 10.1111/j.1349-7006.2011.02050.x. Epub 2011 Sep 1. Cancer Sci. 2011. PMID: 21801281 Free article.
Estrogen receptor (ER) mRNA expression and molecular subtype distribution in ER-negative/progesterone receptor-positive breast cancers.
Itoh M, Iwamoto T, Matsuoka J, Nogami T, Motoki T, Shien T, Taira N, Niikura N, Hayashi N, Ohtani S, Higaki K, Fujiwara T, Doihara H, Symmans WF, Pusztai L. Itoh M, et al. Among authors: nogami t. Breast Cancer Res Treat. 2014 Jan;143(2):403-9. doi: 10.1007/s10549-013-2763-z. Epub 2013 Dec 15. Breast Cancer Res Treat. 2014. PMID: 24337596 Free article.
The estrogen receptor influences microtubule-associated protein tau (MAPT) expression and the selective estrogen receptor inhibitor fulvestrant downregulates MAPT and increases the sensitivity to taxane in breast cancer cells.
Ikeda H, Taira N, Hara F, Fujita T, Yamamoto H, Soh J, Toyooka S, Nogami T, Shien T, Doihara H, Miyoshi S. Ikeda H, et al. Among authors: nogami t. Breast Cancer Res. 2010;12(3):R43. doi: 10.1186/bcr2598. Epub 2010 Jun 28. Breast Cancer Res. 2010. PMID: 20579400 Free PMC article.
180 results