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Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice.
Navab M, Anantharamaiah GM, Reddy ST, Hama S, Hough G, Grijalva VR, Wagner AC, Frank JS, Datta G, Garber D, Fogelman AM. Navab M, et al. Circulation. 2004 Jun 29;109(25):3215-20. doi: 10.1161/01.CIR.0000134275.90823.87. Epub 2004 Jun 14. Circulation. 2004. PMID: 15197147
Apolipoprotein A-I mimetic peptides.
Navab M, Anantharamaiah GM, Reddy ST, Hama S, Hough G, Grijalva VR, Yu N, Ansell BJ, Datta G, Garber DW, Fogelman AM. Navab M, et al. Arterioscler Thromb Vasc Biol. 2005 Jul;25(7):1325-31. doi: 10.1161/01.ATV.0000165694.39518.95. Epub 2005 Apr 14. Arterioscler Thromb Vasc Biol. 2005. PMID: 15831812 Review.
Oral amphipathic peptides as therapeutic agents.
Reddy ST, Anantharamaiah GM, Navab M, Hama S, Hough G, Grijalva V, Garber DW, Datta G, Fogelman AM. Reddy ST, et al. Among authors: grijalva v. Expert Opin Investig Drugs. 2006 Jan;15(1):13-21. doi: 10.1517/13543784.15.1.13. Expert Opin Investig Drugs. 2006. PMID: 16370930 Review.
Apolipoprotein A-I (apoA-I) and apoA-I mimetic peptides inhibit tumor development in a mouse model of ovarian cancer.
Su F, Kozak KR, Imaizumi S, Gao F, Amneus MW, Grijalva V, Ng C, Wagner A, Hough G, Farias-Eisner G, Anantharamaiah GM, Van Lenten BJ, Navab M, Fogelman AM, Reddy ST, Farias-Eisner R. Su F, et al. Among authors: grijalva v. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19997-20002. doi: 10.1073/pnas.1009010107. Epub 2010 Nov 1. Proc Natl Acad Sci U S A. 2010. PMID: 21041624 Free PMC article.
L-5F, an apolipoprotein A-I mimetic, inhibits tumor angiogenesis by suppressing VEGF/basic FGF signaling pathways.
Gao F, Vasquez SX, Su F, Roberts S, Shah N, Grijalva V, Imaizumi S, Chattopadhyay A, Ganapathy E, Meriwether D, Johnston B, Anantharamaiah GM, Navab M, Fogelman AM, Reddy ST, Farias-Eisner R. Gao F, et al. Among authors: grijalva v. Integr Biol (Camb). 2011 Apr;3(4):479-89. doi: 10.1039/c0ib00147c. Epub 2011 Feb 1. Integr Biol (Camb). 2011. PMID: 21283904 Free PMC article.
D-4F, an apoA-I mimetic peptide, inhibits proliferation and tumorigenicity of epithelial ovarian cancer cells by upregulating the antioxidant enzyme MnSOD.
Ganapathy E, Su F, Meriwether D, Devarajan A, Grijalva V, Gao F, Chattopadhyay A, Anantharamaiah GM, Navab M, Fogelman AM, Reddy ST, Farias-Eisner R. Ganapathy E, et al. Among authors: grijalva v. Int J Cancer. 2012 Mar 1;130(5):1071-81. doi: 10.1002/ijc.26079. Epub 2011 May 26. Int J Cancer. 2012. PMID: 21425255 Free PMC article.
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