Le Pecq JB - Search Results

1

Recognition by the DNA repair system of DNA structural alterations induced by reversible drug-DNA interactions.

Lambert B, Segal-Bendirdjian E, Esnault C, Le Pecq JB, Roques BP, Jones B, Yeung AT. Lambert B, et al. Among authors: le pecq jb. Anticancer Drug Des. 1990 Feb;5(1):43-53. Anticancer Drug Des. 1990. PMID: 2180423

2

Selective alteration of mitochondrial function by Ditercalinium (NSC 335153), a DNA bisintercalating agent.

Esnault C, Brown SC, Segal-Bendirdjian E, Coulaud D, Mishal Z, Roques BP, Le Pecq JB. Esnault C, et al. Among authors: le pecq jb. Biochem Pharmacol. 1990 Jan 1;39(1):109-22. doi: 10.1016/0006-2952(90)90654-4. Biochem Pharmacol. 1990. PMID: 2297352

3

The noncovalent complex between DNA and the bifunctional intercalator ditercalinium is a substrate for the UvrABC endonuclease of Escherichia coli.

Lambert B, Jones BK, Roques BP, Le Pecq JB, Yeung AT. Lambert B, et al. Among authors: le pecq jb. Proc Natl Acad Sci U S A. 1989 Sep;86(17):6557-61. doi: 10.1073/pnas.86.17.6557. Proc Natl Acad Sci U S A. 1989. PMID: 2671994 Free PMC article.

4

Induction of an abortive and futile DNA repair process in E. coli by the antitumor DNA bifunctional intercalator, ditercalinium: role in polA in death induction.

Lambert B, Roques BP, Le Pecq JB. Lambert B, et al. Among authors: le pecq jb. Nucleic Acids Res. 1988 Feb 11;16(3):1063-78. doi: 10.1093/nar/16.3.1063. Nucleic Acids Res. 1988. PMID: 2830590 Free PMC article.

5

Selective loss of mitochondrial DNA after treatment of cells with ditercalinium (NSC 335153), an antitumor bis-intercalating agent.

Segal-Bendirdjian E, Coulaud D, Roques BP, Le Pecq JB. Segal-Bendirdjian E, et al. Among authors: le pecq jb. Cancer Res. 1988 Sep 1;48(17):4982-92. Cancer Res. 1988. PMID: 2842043

6

Cytoplasmic accumulation of ditercalinium in rat hepatocytes and induction of mitochondrial damage.

Fellous R, Coulaud D, el Abed I, Roques BP, Le Pecq JB, Delain E, Gouyette A. Fellous R, et al. Among authors: le pecq jb. Cancer Res. 1988 Nov 15;48(22):6542-9. Cancer Res. 1988. PMID: 3180068

7

Relationship between the size and position of substituents on 7H-pyrido[4,3-c]carbazole monomers and dimers and their DNA binding and anti-tumor properties.

Léon P, Garbay-Jaureguiberry C, Le Pecq JB, Roques BP. Léon P, et al. Among authors: le pecq jb. Anticancer Drug Des. 1988 Jun;3(1):1-13. Anticancer Drug Des. 1988. PMID: 3382504

8

DNA bis-intercalators as new anti-tumour agents: modulation of the anti-tumour activity by the linking chain rigidity in the ditercalinium series.

Garbay-Jaureguiberry C, Laugâa P, Delepierre M, Laalami S, Muzard G, Le Pecq JB, Roques BP. Garbay-Jaureguiberry C, et al. Among authors: le pecq jb. Anticancer Drug Des. 1987 Apr;1(4):323-35. Anticancer Drug Des. 1987. PMID: 3450302

9

Removal of DNA curving by DNA ligands: gel electrophoresis study.

Barcelo F, Muzard G, Mendoza R, Révet B, Roques BP, Le Pecq JB. Barcelo F, et al. Among authors: le pecq jb. Biochemistry. 1991 May 21;30(20):4863-73. doi: 10.1021/bi00234a005. Biochemistry. 1991. PMID: 1645181

10

Synthesis and biological activity of new dimers in the 7H-pyrido[4,3-c] carbazole antitumor series.

Garbay-Jaureguiberry C, Barsi MC, Jacquemin-Sablon A, Le Pecq JB, Roques BP. Garbay-Jaureguiberry C, et al. Among authors: le pecq jb. J Med Chem. 1992 Jan;35(1):72-81. doi: 10.1021/jm00079a009. J Med Chem. 1992. PMID: 1732535

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