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The neuroblastoma ALK(I1250T) mutation is a kinase-dead RTK in vitro and in vivo.
Schönherr C, Ruuth K, Eriksson T, Yamazaki Y, Ottmann C, Combaret V, Vigny M, Kamaraj S, Palmer RH, Hallberg B. Schönherr C, et al. Among authors: yamazaki y. Transl Oncol. 2011 Aug;4(4):258-65. doi: 10.1593/tlo.11139. Epub 2011 Aug 1. Transl Oncol. 2011. PMID: 21804922 Free PMC article.
Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma.
Chand D, Yamazaki Y, Ruuth K, Schönherr C, Martinsson T, Kogner P, Attiyeh EF, Maris J, Morozova O, Marra MA, Ohira M, Nakagawara A, Sandström PE, Palmer RH, Hallberg B. Chand D, et al. Among authors: yamazaki y. Dis Model Mech. 2013 Mar;6(2):373-82. doi: 10.1242/dmm.010348. Epub 2012 Oct 25. Dis Model Mech. 2013. PMID: 23104988 Free PMC article.
FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase.
Guan J, Umapathy G, Yamazaki Y, Wolfstetter G, Mendoza P, Pfeifer K, Mohammed A, Hugosson F, Zhang H, Hsu AW, Halenbeck R, Hallberg B, Palmer RH. Guan J, et al. Among authors: yamazaki y. Elife. 2015 Sep 29;4:e09811. doi: 10.7554/eLife.09811. Elife. 2015. PMID: 26418745 Free PMC article.
2,992 results