Dent P - Search Results

1

Disruption of IkappaB kinase (IKK)-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to histone deacetylase (HDAC) inhibitors.

Dai Y, Chen S, Wang L, Pei XY, Funk VL, Kramer LB, Dent P, Grant S. Dai Y, et al. Among authors: dent p. J Biol Chem. 2011 Sep 30;286(39):34036-50. doi: 10.1074/jbc.M111.284216. Epub 2011 Aug 4. J Biol Chem. 2011. PMID: 21816815 Free PMC article.

2

Interruption of the NF-kappaB pathway by Bay 11-7082 promotes UCN-01-mediated mitochondrial dysfunction and apoptosis in human multiple myeloma cells.

Dai Y, Pei XY, Rahmani M, Conrad DH, Dent P, Grant S. Dai Y, et al. Among authors: dent p. Blood. 2004 Apr 1;103(7):2761-70. doi: 10.1182/blood-2003-09-3037. Epub 2003 Nov 26. Blood. 2004. PMID: 14645003 Free article.

3

A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2.

Dai Y, Rahmani M, Corey SJ, Dent P, Grant S. Dai Y, et al. Among authors: dent p. J Biol Chem. 2004 Aug 13;279(33):34227-39. doi: 10.1074/jbc.M402290200. Epub 2004 Jun 2. J Biol Chem. 2004. PMID: 15175350 Free article.

4

Contribution of disruption of the nuclear factor-kappaB pathway to induction of apoptosis in human leukemia cells by histone deacetylase inhibitors and flavopiridol.

Gao N, Dai Y, Rahmani M, Dent P, Grant S. Gao N, et al. Among authors: dent p. Mol Pharmacol. 2004 Oct;66(4):956-63. doi: 10.1124/mol.104.002014. Epub 2004 Jul 2. Mol Pharmacol. 2004. PMID: 15235103

5

Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.

Rahmani M, Reese E, Dai Y, Bauer C, Payne SG, Dent P, Spiegel S, Grant S. Rahmani M, et al. Among authors: dent p. Cancer Res. 2005 Mar 15;65(6):2422-32. doi: 10.1158/0008-5472.CAN-04-2440. Cancer Res. 2005. PMID: 15781658

6

The farnesyltransferase inhibitor L744832 potentiates UCN-01-induced apoptosis in human multiple myeloma cells.

Pei XY, Dai Y, Rahmani M, Li W, Dent P, Grant S. Pei XY, et al. Among authors: dent p. Clin Cancer Res. 2005 Jun 15;11(12):4589-600. doi: 10.1158/1078-0432.CCR-04-2346. Clin Cancer Res. 2005. PMID: 15958645

7

Blockade of histone deacetylase inhibitor-induced RelA/p65 acetylation and NF-kappaB activation potentiates apoptosis in leukemia cells through a process mediated by oxidative damage, XIAP downregulation, and c-Jun N-terminal kinase 1 activation.

Dai Y, Rahmani M, Dent P, Grant S. Dai Y, et al. Among authors: dent p. Mol Cell Biol. 2005 Jul;25(13):5429-44. doi: 10.1128/MCB.25.13.5429-5444.2005. Mol Cell Biol. 2005. PMID: 15964800 Free PMC article.

8

Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation.

Rahmani M, Davis EM, Bauer C, Dent P, Grant S. Rahmani M, et al. Among authors: dent p. J Biol Chem. 2005 Oct 21;280(42):35217-27. doi: 10.1074/jbc.M506551200. Epub 2005 Aug 18. J Biol Chem. 2005. PMID: 16109713 Free article.

9

Cyclin D1 overexpression increases the susceptibility of human U266 myeloma cells to CDK inhibitors through a process involving p130-, p107- and E2F-dependent S phase entry.

Dai Y, Hamm TE, Dent P, Grant S. Dai Y, et al. Among authors: dent p. Cell Cycle. 2006 Feb;5(4):437-46. doi: 10.4161/cc.5.4.2441. Epub 2006 Feb 15. Cell Cycle. 2006. PMID: 16479154

10

Dissecting the roles of checkpoint kinase 1/CDC2 and mitogen-activated protein kinase kinase 1/2/extracellular signal-regulated kinase 1/2 in relation to 7-hydroxystaurosporine-induced apoptosis in human multiple myeloma cells.

Pei XY, Li W, Dai Y, Dent P, Grant S. Pei XY, et al. Among authors: dent p. Mol Pharmacol. 2006 Dec;70(6):1965-73. doi: 10.1124/mol.106.028373. Epub 2006 Aug 29. Mol Pharmacol. 2006. PMID: 16940414

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