Lodola A - Search Results

1

Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: steric effects of N-alkyl chain on rat plasma and liver stability.

Vacondio F, Silva C, Lodola A, Carmi C, Rivara S, Duranti A, Tontini A, Sanchini S, Clapper JR, Piomelli D, Tarzia G, Mor M. Vacondio F, et al. Among authors: lodola a. Eur J Med Chem. 2011 Sep;46(9):4466-73. doi: 10.1016/j.ejmech.2011.07.021. Epub 2011 Jul 21. Eur J Med Chem. 2011. PMID: 21820769 Free PMC article.

2

Synthesis, pharmacological evaluation, and structure-activity relationships of benzopyran derivatives with potent SERM activity.

Amari G, Armani E, Ghirardi S, Delcanale M, Civelli M, Caruso PL, Galbiati E, Lipreri M, Rivara S, Lodola A, Mor M. Amari G, et al. Among authors: lodola a. Bioorg Med Chem. 2004 Jul 15;12(14):3763-82. doi: 10.1016/j.bmc.2004.05.015. Bioorg Med Chem. 2004. PMID: 15210143

3

Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies.

Mor M, Rivara S, Lodola A, Plazzi PV, Tarzia G, Duranti A, Tontini A, Piersanti G, Kathuria S, Piomelli D. Mor M, et al. Among authors: lodola a. J Med Chem. 2004 Oct 7;47(21):4998-5008. doi: 10.1021/jm031140x. J Med Chem. 2004. PMID: 15456244 Free article.

4

QM/MM modelling of oleamide hydrolysis in fatty acid amide hydrolase (FAAH) reveals a new mechanism of nucleophile activation.

Lodola A, Mor M, Hermann JC, Tarzia G, Piomelli D, Mulholland AJ. Lodola A, et al. Chem Commun (Camb). 2005 Sep 21;(35):4399-401. doi: 10.1039/b503887a. Epub 2005 Jul 11. Chem Commun (Camb). 2005. PMID: 16136230 Free article.

5

5-benzylidene-hydantoins as new EGFR inhibitors with antiproliferative activity.

Carmi C, Cavazzoni A, Zuliani V, Lodola A, Bordi F, Plazzi PV, Alfieri RR, Petronini PG, Mor M. Carmi C, et al. Among authors: lodola a. Bioorg Med Chem Lett. 2006 Aug 1;16(15):4021-5. doi: 10.1016/j.bmcl.2006.05.010. Epub 2006 May 19. Bioorg Med Chem Lett. 2006. PMID: 16713265

6

Synthesis and structure-activity relationships of FAAH inhibitors: cyclohexylcarbamic acid biphenyl esters with chemical modulation at the proximal phenyl ring.

Tarzia G, Duranti A, Gatti G, Piersanti G, Tontini A, Rivara S, Lodola A, Plazzi PV, Mor M, Kathuria S, Piomelli D. Tarzia G, et al. Among authors: lodola a. ChemMedChem. 2006 Jan;1(1):130-9. doi: 10.1002/cmdc.200500017. ChemMedChem. 2006. PMID: 16892344

7

Conformational effects in enzyme catalysis: reaction via a high energy conformation in fatty acid amide hydrolase.

Lodola A, Mor M, Zurek J, Tarzia G, Piomelli D, Harvey JN, Mulholland AJ. Lodola A, et al. Biophys J. 2007 Jan 15;92(2):L20-2. doi: 10.1529/biophysj.106.098434. Epub 2006 Nov 10. Biophys J. 2007. PMID: 17098788 Free PMC article.

8

Design and synthesis of N-(3,3-diphenylpropenyl)alkanamides as a novel class of high-affinity MT2-selective melatonin receptor ligands.

Bedini A, Spadoni G, Gatti G, Lucarini S, Tarzia G, Rivara S, Lorenzi S, Lodola A, Mor M, Lucini V, Pannacci M, Scaglione F. Bedini A, et al. Among authors: lodola a. J Med Chem. 2006 Dec 14;49(25):7393-403. doi: 10.1021/jm060850a. J Med Chem. 2006. PMID: 17149869

9

Application of 3D-QSAR in the rational design of receptor ligands and enzyme inhibitors.

Mor M, Rivara S, Lodola A, Lorenzi S, Bordi F, Plazzi PV, Spadoni G, Bedini A, Duranti A, Tontini A, Tarzia G. Mor M, et al. Among authors: lodola a. Chem Biodivers. 2005 Nov;2(11):1438-51. doi: 10.1002/cbdv.200590117. Chem Biodivers. 2005. PMID: 17191945

10

Synthesis, enantiomeric resolution, and structure-activity relationship study of a series of 10,11-dihydro-5H-dibenzo[a,d]cycloheptene MT2 receptor antagonists.

Spadoni G, Bedini A, Diamantini G, Tarzia G, Rivara S, Lorenzi S, Lodola A, Mor M, Lucini V, Pannacci M, Caronno A, Fraschini F. Spadoni G, et al. Among authors: lodola a. ChemMedChem. 2007 Dec;2(12):1741-9. doi: 10.1002/cmdc.200700141. ChemMedChem. 2007. PMID: 17907131

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