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Single and combination herpes simplex virus type 2 glycoprotein vaccines adjuvanted with CpG oligodeoxynucleotides or monophosphoryl lipid A exhibit differential immunity that is not correlated to protection in animal models.
Khodai T, Chappell D, Christy C, Cockle P, Eyles J, Hammond D, Gore K, McCluskie MJ, Evans DM, Lang S, Loudon PT, Townend T, Wright P, West K, Bright H. Khodai T, et al. Among authors: eyles j. Clin Vaccine Immunol. 2011 Oct;18(10):1702-9. doi: 10.1128/CVI.05071-11. Epub 2011 Aug 18. Clin Vaccine Immunol. 2011. PMID: 21852545 Free PMC article.
Nonreplicating vaccines can protect african green monkeys from the memphis 37 strain of respiratory syncytial virus.
Eyles JE, Johnson JE, Megati S, Roopchand V, Cockle PJ, Weeratna R, Makinen S, Brown TP, Lang S, Witko SE, Kotash CS, Li J, West K, Maldonado O, Falconer DJ, Lees C, Smith GJ, White P, Wright P, Loudon PT, Merson JR, Jansen KU, Sidhu MK. Eyles JE, et al. J Infect Dis. 2013 Jul 15;208(2):319-29. doi: 10.1093/infdis/jit169. Epub 2013 Apr 17. J Infect Dis. 2013. PMID: 23596321
273 results