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Minor grove binding ligands disrupt PARP-1 activation pathways.
Kirsanov KI, Kotova E, Makhov P, Golovine K, Lesovaya EA, Kolenko VM, Yakubovskaya MG, Tulin AV. Kirsanov KI, et al. Among authors: makhov p. Oncotarget. 2014 Jan 30;5(2):428-37. doi: 10.18632/oncotarget.1742. Oncotarget. 2014. PMID: 24504413 Free PMC article.
PPP2R2A prostate cancer haploinsufficiency is associated with worse prognosis and a high vulnerability to B55α/PP2A reconstitution that triggers centrosome destabilization.
Zhao Z, Kurimchak A, Nikonova AS, Feiser F, Wasserman JS, Fowle H, Varughese T, Connors M, Johnson K, Makhov P, Lindskog C, Kolenko VM, Golemis EA, Duncan JS, Graña X. Zhao Z, et al. Among authors: makhov p. Oncogenesis. 2019 Dec 10;8(12):72. doi: 10.1038/s41389-019-0180-9. Oncogenesis. 2019. PMID: 31822657 Free PMC article.
Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC).
Makhov P, Bychkov I, Faezov B, Deneka A, Kudinov A, Nicolas E, Brebion R, Avril E, Cai KQ, Kharin LV, Voloshin M, Frantsiyants E, Karnaukhov N, Kit OI, Topchu I, Fazliyeva R, Nikonova AS, Serebriiskii IG, Borghaei H, Edelman M, Dulaimi E, Golemis EA, Boumber Y. Makhov P, et al. Oncogenesis. 2021 Mar 15;10(3):29. doi: 10.1038/s41389-021-00317-y. Oncogenesis. 2021. PMID: 33723247 Free PMC article.
IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma.
Aghayev T, Mazitova AM, Fang JR, Peshkova IO, Rausch M, Hung M, White KF, Masia R, Titerina EK, Fatkhullina AR, Cousineau I, Turcotte S, Zhigarev D, Marchenko A, Khoziainova S, Makhov P, Tan YF, Kossenkov AV, Wiest DL, Stagg J, Wang XW, Campbell KS, Dzutsev AK, Trinchieri G, Hill JA, Grivennikov SI, Koltsova EK. Aghayev T, et al. Among authors: makhov p. Cancer Discov. 2022 Aug 5;12(8):1960-1983. doi: 10.1158/2159-8290.CD-20-1628. Cancer Discov. 2022. PMID: 35723626 Free PMC article.
52 results