Tepe JJ - Search Results

1

Current inhibitors of checkpoint kinase 2.

Nguyen TN, Tepe JJ. Nguyen TN, et al. Among authors: tepe jj. Curr Med Chem. 2011;18(28):4368-74. doi: 10.2174/092986711797200390. Curr Med Chem. 2011. PMID: 21861812 Review.

2

Inhibition of cytokine production by hymenialdisine derivatives.

Sharma V, Lansdell TA, Jin G, Tepe JJ. Sharma V, et al. Among authors: tepe jj. J Med Chem. 2004 Jul 1;47(14):3700-3. doi: 10.1021/jm040013d. J Med Chem. 2004. PMID: 15214798

3

Potent inhibition of checkpoint kinase activity by a hymenialdisine-derived indoloazepine.

Sharma V, Tepe JJ. Sharma V, et al. Among authors: tepe jj. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4319-21. doi: 10.1016/j.bmcl.2004.05.079. Bioorg Med Chem Lett. 2004. PMID: 15261294

4

Sensitization of tumor cells toward chemotherapy: enhancing the efficacy of camptothecin with imidazolines.

Sharma V, Lansdell TA, Peddibhotla S, Tepe JJ. Sharma V, et al. Among authors: tepe jj. Chem Biol. 2004 Dec;11(12):1689-99. doi: 10.1016/j.chembiol.2004.10.006. Chem Biol. 2004. PMID: 15610853

5

Enhancement of chemotherapeutic efficacy by small molecule inhibition of NF-kappaB and checkpoint kinases.

Sharma V, Hupp CD, Tepe JJ. Sharma V, et al. Among authors: tepe jj. Curr Med Chem. 2007;14(10):1061-74. doi: 10.2174/092986707780362844. Curr Med Chem. 2007. PMID: 17456020 Review.

6

Nuclear factor-kappaB mediated inhibition of cytokine production by imidazoline scaffolds.

Kahlon DK, Lansdell TA, Fisk JS, Hupp CD, Friebe TL, Hovde S, Jones AD, Dyer RD, Henry RW, Tepe JJ. Kahlon DK, et al. Among authors: tepe jj. J Med Chem. 2009 Mar 12;52(5):1302-9. doi: 10.1021/jm8013162. J Med Chem. 2009. PMID: 19220017

7

Structural-activity relationship study of highly-functionalized imidazolines as potent inhibitors of nuclear transcription factor-kappaB mediated IL-6 production.

Kahlon DK, Lansdell TA, Fisk JS, Tepe JJ. Kahlon DK, et al. Among authors: tepe jj. Bioorg Med Chem. 2009 Apr 15;17(8):3093-103. doi: 10.1016/j.bmc.2009.03.002. Epub 2009 Mar 9. Bioorg Med Chem. 2009. PMID: 19328000

8

Preparation of hymenialdisine, analogues and their evaluation as kinase inhibitors.

Nguyen TN, Tepe JJ. Nguyen TN, et al. Among authors: tepe jj. Curr Med Chem. 2009;16(24):3122-43. doi: 10.2174/092986709788803015. Curr Med Chem. 2009. PMID: 19689287 Review.

9

Radioprotection by hymenialdisine-derived checkpoint kinase 2 inhibitors.

Nguyen TN, Saleem RS, Luderer MJ, Hovde S, Henry RW, Tepe JJ. Nguyen TN, et al. Among authors: tepe jj. ACS Chem Biol. 2012 Jan 20;7(1):172-84. doi: 10.1021/cb200320c. Epub 2011 Oct 24. ACS Chem Biol. 2012. PMID: 22004065

10

Synthesis and evaluation of debromohymenialdisine-derived Chk2 inhibitors.

Saleem RS, Lansdell TA, Tepe JJ. Saleem RS, et al. Among authors: tepe jj. Bioorg Med Chem. 2012 Feb 15;20(4):1475-81. doi: 10.1016/j.bmc.2011.12.054. Epub 2012 Jan 11. Bioorg Med Chem. 2012. PMID: 22285028

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