Freel Meyers CL - Search Results

1

Bisphosphonamidate clodronate prodrug exhibits potent anticancer activity in non-small-cell lung cancer cells.

Webster MR, Zhao M, Rudek MA, Hann CL, Freel Meyers CL. Webster MR, et al. Among authors: freel meyers cl. J Med Chem. 2011 Oct 13;54(19):6647-56. doi: 10.1021/jm200521a. Epub 2011 Sep 9. J Med Chem. 2011. PMID: 21863853 Free PMC article.

2

Bisphosphonamidate clodronate prodrug exhibits selective cytotoxic activity against melanoma cell lines.

Webster MR, Kamat C, Connis N, Zhao M, Weeraratna AT, Rudek MA, Hann CL, Freel Meyers CL. Webster MR, et al. Among authors: freel meyers cl. Mol Cancer Ther. 2014 Feb;13(2):297-306. doi: 10.1158/1535-7163.MCT-13-0315. Epub 2013 Dec 5. Mol Cancer Ther. 2014. PMID: 24310621 Free PMC article.

3

Synthesis and biological activity of novel 5-fluoro-2'-deoxyuridine phosphoramidate prodrugs.

Freel Meyers CL, Hong L, Joswig C, Borch RF. Freel Meyers CL, et al. J Med Chem. 2000 Nov 2;43(22):4313-8. doi: 10.1021/jm000301j. J Med Chem. 2000. PMID: 11063625

4

Versatile (1)H-(31)P-(31)P COSY 2D NMR techniques for the characterization of polyphosphorylated small molecules.

Majumdar A, Sun Y, Shah M, Freel Meyers CL. Majumdar A, et al. Among authors: freel meyers cl. J Org Chem. 2010 May 21;75(10):3214-23. doi: 10.1021/jo100042m. J Org Chem. 2010. PMID: 20408590 Free PMC article.

5

Synthesis and Evaluation of Fluoroalkyl Phosphonyl Analogues of 2- C-Methylerythritol Phosphate as Substrates and Inhibitors of IspD from Human Pathogens.

Bartee D, Wheadon MJ, Freel Meyers CL. Bartee D, et al. Among authors: freel meyers cl. J Org Chem. 2018 Sep 7;83(17):9580-9591. doi: 10.1021/acs.joc.8b00686. Epub 2018 Jun 11. J Org Chem. 2018. PMID: 29870251 Free PMC article.

6

Activation mechanisms of nucleoside phosphoramidate prodrugs.

Freel Meyers CL, Borch RF. Freel Meyers CL, et al. J Med Chem. 2000 Nov 2;43(22):4319-27. doi: 10.1021/jm000302b. J Med Chem. 2000. PMID: 11063626

7

Antibiotic glycosyltransferases: antibiotic maturation and prospects for reprogramming.

Walsh C, Freel Meyers CL, Losey HC. Walsh C, et al. Among authors: freel meyers cl. J Med Chem. 2003 Jul 31;46(16):3425-36. doi: 10.1021/jm030257i. J Med Chem. 2003. PMID: 12877577 Review. No abstract available.

8

Enamide Prodrugs of Acetyl Phosphonate Deoxy-d-xylulose-5-phosphate Synthase Inhibitors as Potent Antibacterial Agents.

Bartee D, Sanders S, Phillips PD, Harrison MJ, Koppisch AT, Freel Meyers CL. Bartee D, et al. Among authors: freel meyers cl. ACS Infect Dis. 2019 Mar 8;5(3):406-417. doi: 10.1021/acsinfecdis.8b00307. Epub 2019 Jan 18. ACS Infect Dis. 2019. PMID: 30614674 Free PMC article.

9

Linear and branched polymer prodrugs of the water-soluble nucleoside reverse-transcriptase inhibitor emtricitabine as structural materials for long-acting implants.

Shakil A, Hern FY, Liu C, Temburnikar K, Chambon P, Liptrott N, McDonald TO, Neary M, Owen A, Freel Meyers C, Rannard SP. Shakil A, et al. J Mater Chem B. 2022 Jun 15;10(23):4395-4404. doi: 10.1039/d2tb00825d. J Mater Chem B. 2022. PMID: 35604111 Free PMC article.

10

Resistance to the antimicrobial agent fosmidomycin and an FR900098 prodrug through mutations in the deoxyxylulose phosphate reductoisomerase gene (dxr).

Armstrong CM, Meyers DJ, Imlay LS, Freel Meyers C, Odom AR. Armstrong CM, et al. Antimicrob Agents Chemother. 2015 Sep;59(9):5511-9. doi: 10.1128/AAC.00602-15. Epub 2015 Jun 29. Antimicrob Agents Chemother. 2015. PMID: 26124156 Free PMC article.

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