Arkin S - Search Results

1

Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib.

Cortes JE, Kantarjian HM, Brümmendorf TH, Kim DW, Turkina AG, Shen ZX, Pasquini R, Khoury HJ, Arkin S, Volkert A, Besson N, Abbas R, Wang J, Leip E, Gambacorti-Passerini C. Cortes JE, et al. Among authors: arkin s. Blood. 2011 Oct 27;118(17):4567-76. doi: 10.1182/blood-2011-05-355594. Epub 2011 Aug 24. Blood. 2011. PMID: 21865346 Free PMC article. Clinical Trial.

2

Bosutinib versus Placebo for Autosomal Dominant Polycystic Kidney Disease.

Tesar V, Ciechanowski K, Pei Y, Barash I, Shannon M, Li R, Williams JH, Levisetti M, Arkin S, Serra A. Tesar V, et al. Among authors: arkin s. J Am Soc Nephrol. 2017 Nov;28(11):3404-3413. doi: 10.1681/ASN.2016111232. Epub 2017 Aug 24. J Am Soc Nephrol. 2017. PMID: 28838955 Free PMC article. Clinical Trial.

3

Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.

Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators. Salloway S, et al. N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839. N Engl J Med. 2014. PMID: 24450891 Free PMC article. Clinical Trial.

4

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Domagrozumab (PF-06252616), an Antimyostatin Monoclonal Antibody, in Healthy Subjects.

Bhattacharya I, Pawlak S, Marraffino S, Christensen J, Sherlock SP, Alvey C, Morris C, Arkin S, Binks M. Bhattacharya I, et al. Among authors: arkin s. Clin Pharmacol Drug Dev. 2018 Jun;7(5):484-497. doi: 10.1002/cpdd.386. Epub 2017 Sep 7. Clin Pharmacol Drug Dev. 2018. PMID: 28881472 Clinical Trial.

5

A first-in-human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of PF-06741086, an anti-tissue factor pathway inhibitor mAb, in healthy volunteers.

Cardinal M, Kantaridis C, Zhu T, Sun P, Pittman DD, Murphy JE, Arkin S. Cardinal M, et al. Among authors: arkin s. J Thromb Haemost. 2018 Sep;16(9):1722-1731. doi: 10.1111/jth.14207. Epub 2018 Jul 20. J Thromb Haemost. 2018. PMID: 29908043 Free article. Clinical Trial.

6

Phase 1 dose-escalating study to evaluate the safety, pharmacokinetics, and pharmacodynamics of a recombinant factor Xa variant (FXa^I16L ).

Parsons-Rich D, Hua F, Li G, Kantaridis C, Pittman DD, Arkin S. Parsons-Rich D, et al. Among authors: arkin s. J Thromb Haemost. 2017 May;15(5):931-937. doi: 10.1111/jth.13673. Epub 2017 Apr 25. J Thromb Haemost. 2017. PMID: 28294526 Free article. Clinical Trial.

7

Activated recombinant human coagulation factor VII therapy for intracranial hemorrhage in patients with hemophilia A or B with inhibitors. Results of the novoseven emergency-use program.

Arkin S, Cooper HA, Hutter JJ, Miller S, Schmidt ML, Seibel NL, Shapiro A, Warrier I. Arkin S, et al. Haemostasis. 1998 Mar-Apr;28(2):93-8. doi: 10.1159/000022418. Haemostasis. 1998. PMID: 10087434 Clinical Trial.

8

Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A. Safety, efficacy, and development of inhibitors. Kogenate Previously Untreated Patient Study Group.

Lusher JM, Arkin S, Abildgaard CF, Schwartz RS. Lusher JM, et al. Among authors: arkin s. N Engl J Med. 1993 Feb 18;328(7):453-9. doi: 10.1056/NEJM199302183280701. N Engl J Med. 1993. PMID: 8421474 Free article. Clinical Trial.

9

MR imaging of deferoxamine-induced bone dysplasia in an 8-year-old female with thalassemia major.

Miller TT, Caldwell G, Kaye JJ, Arkin S, Burke S, Brill PW. Miller TT, et al. Among authors: arkin s. Pediatr Radiol. 1993;23(7):523-4. doi: 10.1007/BF02012138. Pediatr Radiol. 1993. PMID: 8309753

10

Clinical efficacy of recombinant factor VIII. The rFactor VIII Clinical Trial Group.

Arkin S, Rose E, Forster A, Aledort LM. Arkin S, et al. Semin Hematol. 1991 Apr;28(2 Suppl 1):47-51. Semin Hematol. 1991. PMID: 1908129 Clinical Trial.

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