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Gene therapy targets in heart failure: the path to translation.
Raake PW, Tscheschner H, Reinkober J, Ritterhoff J, Katus HA, Koch WJ, Most P. Raake PW, et al. Among authors: reinkober j. Clin Pharmacol Ther. 2011 Oct;90(4):542-53. doi: 10.1038/clpt.2011.148. Epub 2011 Aug 24. Clin Pharmacol Ther. 2011. PMID: 21866097 Free PMC article. Review.
AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model.
Raake PW, Schlegel P, Ksienzyk J, Reinkober J, Barthelmes J, Schinkel S, Pleger S, Mier W, Haberkorn U, Koch WJ, Katus HA, Most P, Müller OJ. Raake PW, et al. Among authors: reinkober j. Eur Heart J. 2013 May;34(19):1437-47. doi: 10.1093/eurheartj/ehr447. Epub 2012 Jan 19. Eur Heart J. 2013. PMID: 22261894 Free PMC article.
G protein-coupled receptor kinase 2 promotes cardiac hypertrophy.
Schlegel P, Reinkober J, Meinhardt E, Tscheschner H, Gao E, Schumacher SM, Yuan A, Backs J, Most P, Wieland T, Koch WJ, Katus HA, Raake PW. Schlegel P, et al. Among authors: reinkober j. PLoS One. 2017 Jul 31;12(7):e0182110. doi: 10.1371/journal.pone.0182110. eCollection 2017. PLoS One. 2017. PMID: 28759639 Free PMC article.