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N'-(arylsulfonyl)pyrazoline-1-carboxamidines as novel, neutral 5-hydroxytryptamine 6 receptor (5-HT₆R) antagonists with unique structural features.
van Loevezijn A, Venhorst J, Iwema Bakker WI, de Korte CG, de Looff W, Verhoog S, van Wees JW, van Hoeve M, van de Woestijne RP, van der Neut MA, Borst AJ, van Dongen MJ, de Bruin NM, Keizer HG, Kruse CG. van Loevezijn A, et al. Among authors: van dongen mj. J Med Chem. 2011 Oct 27;54(20):7030-54. doi: 10.1021/jm200466r. Epub 2011 Sep 26. J Med Chem. 2011. PMID: 21866910
Assignment of the orphan nuclear receptor Nurr1 by NMR.
Michiels P, Atkins K, Ludwig C, Whittaker S, van Dongen M, Günther U. Michiels P, et al. Biomol NMR Assign. 2010 Apr;4(1):101-5. doi: 10.1007/s12104-010-9210-4. Epub 2010 Mar 19. Biomol NMR Assign. 2010. PMID: 20300892
Site-selective labeling strategies for screening by NMR.
Weigelt J, Wikström M, Schultz J, van Dongen MJ. Weigelt J, et al. Among authors: van dongen mj. Comb Chem High Throughput Screen. 2002 Dec;5(8):623-30. doi: 10.2174/1386207023329978. Comb Chem High Throughput Screen. 2002. PMID: 12470259 Review.
Structure-based screening and design in drug discovery.
van Dongen M, Weigelt J, Uppenberg J, Schultz J, Wikström M. van Dongen M, et al. Drug Discov Today. 2002 Apr 15;7(8):471-8. doi: 10.1016/s1359-6446(02)02233-x. Drug Discov Today. 2002. PMID: 11965396 Review.
23 results