Khosla C - Search Results

1

Analysis of the ketosynthase-chain length factor heterodimer from the fredericamycin polyketide synthase.

Szu PH, Govindarajan S, Meehan MJ, Das A, Nguyen DD, Dorrestein PC, Minshull J, Khosla C. Szu PH, et al. Among authors: khosla c. Chem Biol. 2011 Aug 26;18(8):1021-31. doi: 10.1016/j.chembiol.2011.07.015. Chem Biol. 2011. PMID: 21867917 Free PMC article.

2

Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase.

McDaniel R, Ebert-Khosla S, Fu H, Hopwood DA, Khosla C. McDaniel R, et al. Among authors: khosla c. Proc Natl Acad Sci U S A. 1994 Nov 22;91(24):11542-6. doi: 10.1073/pnas.91.24.11542. Proc Natl Acad Sci U S A. 1994. PMID: 7972098 Free PMC article.

3

A functional chimeric modular polyketide synthase generated via domain replacement.

Bedford D, Jacobsen JR, Luo G, Cane DE, Khosla C. Bedford D, et al. Among authors: khosla c. Chem Biol. 1996 Oct;3(10):827-31. doi: 10.1016/s1074-5521(96)90068-x. Chem Biol. 1996. PMID: 8939701

4

Domain analysis of the molecular recognition features of aromatic polyketide synthase subunits.

Zawada RJ, Khosla C. Zawada RJ, et al. Among authors: khosla c. J Biol Chem. 1997 Jun 27;272(26):16184-8. doi: 10.1074/jbc.272.26.16184. J Biol Chem. 1997. PMID: 9195917 Free article.

5

Engineered intermodular and intramodular polyketide synthase fusions.

McDaniel R, Kao CM, Hwang SJ, Khosla C. McDaniel R, et al. Among authors: khosla c. Chem Biol. 1997 Sep;4(9):667-74. doi: 10.1016/s1074-5521(97)90222-2. Chem Biol. 1997. PMID: 9331407

6

Molecular recognition of diketide substrates by a beta-ketoacyl-acyl carrier protein synthase domain within a bimodular polyketide synthase.

Chuck JA, McPherson M, Huang H, Jacobsen JR, Khosla C, Cane DE. Chuck JA, et al. Among authors: khosla c. Chem Biol. 1997 Oct;4(10):757-66. doi: 10.1016/s1074-5521(97)90314-8. Chem Biol. 1997. PMID: 9375254

7

Engineered biosynthesis of novel polyketides: evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursor.

Fu H, Hopwood DA, Khosla C. Fu H, et al. Among authors: khosla c. Chem Biol. 1994 Dec;1(4):205-10. doi: 10.1016/1074-5521(94)90012-4. Chem Biol. 1994. PMID: 9383392

8

Combinatorial biosynthesis of 'unnatural' natural products: the polyketide example.

Tsoi CJ, Khosla C. Tsoi CJ, et al. Among authors: khosla c. Chem Biol. 1995 Jun;2(6):355-62. doi: 10.1016/1074-5521(95)90214-7. Chem Biol. 1995. PMID: 9383437 Review.

9

Purification and in vitro reconstitution of the essential protein components of an aromatic polyketide synthase.

Carreras CW, Khosla C. Carreras CW, et al. Among authors: khosla c. Biochemistry. 1998 Feb 24;37(8):2084-8. doi: 10.1021/bi972919+. Biochemistry. 1998. PMID: 9518007

10

Precursor-directed biosynthesis of 12-ethyl erythromycin.

Jacobsen JR, Keatinge-Clay AT, Cane DE, Khosla C. Jacobsen JR, et al. Among authors: khosla c. Bioorg Med Chem. 1998 Aug;6(8):1171-7. doi: 10.1016/s0968-0896(98)00081-9. Bioorg Med Chem. 1998. PMID: 9784859 Free article.

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