Colagiovanni DB - Search Results

1

Preclinical 28-day inhalation toxicity assessment of s-nitrosoglutathione in beagle dogs and Wistar rats.

Colagiovanni DB, Borkhataria D, Looker D, Schuler D, Bachmann C, Sagelsdorff P, Honarvar N, Rosenthal GJ. Colagiovanni DB, et al. Int J Toxicol. 2011 Oct;30(5):466-77. doi: 10.1177/1091581811412084. Epub 2011 Aug 25. Int J Toxicol. 2011. PMID: 21868767

2

A nonclinical safety and pharmacokinetic evaluation of N6022: a first-in-class S-nitrosoglutathione reductase inhibitor for the treatment of asthma.

Colagiovanni DB, Drolet DW, Langlois-Forget E, Piché MP, Looker D, Rosenthal GJ. Colagiovanni DB, et al. Regul Toxicol Pharmacol. 2012 Feb;62(1):115-24. doi: 10.1016/j.yrtph.2011.12.012. Epub 2011 Dec 24. Regul Toxicol Pharmacol. 2012. PMID: 22210450

3

Discovery of potent and novel S-nitrosoglutathione reductase inhibitors devoid of cytochrome P450 activities.

Sun X, Qiu J, Strong SA, Green LS, Wasley JW, Blonder JP, Colagiovanni DB, Mutka SC, Stout AM, Richards JP, Rosenthal GJ. Sun X, et al. Among authors: colagiovanni db. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5849-53. doi: 10.1016/j.bmcl.2011.07.103. Epub 2011 Aug 3. Bioorg Med Chem Lett. 2011. PMID: 21855338

4

Structure-activity relationship of pyrrole based S-nitrosoglutathione reductase inhibitors: carboxamide modification.

Sun X, Qiu J, Strong SA, Green LS, Wasley JW, Blonder JP, Colagiovanni DB, Stout AM, Mutka SC, Richards JP, Rosenthal GJ. Sun X, et al. Among authors: colagiovanni db. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2338-42. doi: 10.1016/j.bmcl.2012.01.047. Epub 2012 Feb 2. Bioorg Med Chem Lett. 2012. PMID: 22342142

5

Structure-activity relationships of pyrrole based S-nitrosoglutathione reductase inhibitors: pyrrole regioisomers and propionic acid replacement.

Sun X, Qiu J, Strong SA, Green LS, Wasley JW, Colagiovanni DB, Mutka SC, Blonder JP, Stout AM, Richards JP, Chun L, Rosenthal GJ. Sun X, et al. Among authors: colagiovanni db. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3671-5. doi: 10.1016/j.bmcl.2011.04.086. Epub 2011 Apr 24. Bioorg Med Chem Lett. 2011. PMID: 21570838

6

Discovery of s-nitrosoglutathione reductase inhibitors: potential agents for the treatment of asthma and other inflammatory diseases.

Sun X, Wasley JW, Qiu J, Blonder JP, Stout AM, Green LS, Strong SA, Colagiovanni DB, Richards JP, Mutka SC, Chun L, Rosenthal GJ. Sun X, et al. Among authors: colagiovanni db. ACS Med Chem Lett. 2011 Mar 11;2(5):402-6. doi: 10.1021/ml200045s. eCollection 2011 May 12. ACS Med Chem Lett. 2011. PMID: 24900320 Free PMC article.

7

Safety assessment of 4'-thio-beta-D-arabinofuranosylcytosine in the beagle dog suggests a drug-induced centrally mediated effect on the hypothalamic-pituitary-adrenal axis.

Colagiovanni DB, Drolet DW, Dihel L, Meyer DJ, Hart K, Wolf J. Colagiovanni DB, et al. Int J Toxicol. 2006 Mar-Apr;25(2):119-26. doi: 10.1080/10915810600605898. Int J Toxicol. 2006. PMID: 16597550

8

S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury.

Cox AG, Saunders DC, Kelsey PB Jr, Conway AA, Tesmenitsky Y, Marchini JF, Brown KK, Stamler JS, Colagiovanni DB, Rosenthal GJ, Croce KJ, North TE, Goessling W. Cox AG, et al. Among authors: colagiovanni db. Cell Rep. 2014 Jan 16;6(1):56-69. doi: 10.1016/j.celrep.2013.12.007. Epub 2014 Jan 2. Cell Rep. 2014. PMID: 24388745 Free PMC article.

9

Pharmacokinetics, safety, and efficacy of a liposome encapsulated thymidylate synthase inhibitor, OSI-7904L [(S)-2-[5-[(1,2-dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl]amino-1-oxo-2-isoindolynl]-glutaric acid] in mice.

Desjardins J, Emerson DL, Colagiovanni DB, Abbott E, Brown EN, Drolet DW. Desjardins J, et al. Among authors: colagiovanni db. J Pharmacol Exp Ther. 2004 Jun;309(3):894-902. doi: 10.1124/jpet.103.064725. Epub 2004 Feb 24. J Pharmacol Exp Ther. 2004. PMID: 14982966

10

High gamma-glutamyltransferase (GGT) activity in human breast milk confounds interpretation of high serum GGT activity in a nursing infant with liver disease.

Colagiovanni DB, Meyer DJ, Wolf JM, Hart K, Abbott E, Santos C. Colagiovanni DB, et al. Clin Chem. 2005 Sep;51(9):1750-1. doi: 10.1373/clinchem.2005.053819. Clin Chem. 2005. PMID: 16120961 No abstract available.

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