D'hooghe M - Search Results

1

Straightforward synthesis of 1-alkyl-2-(trifluoromethyl)aziridines starting from 1,1,1-trifluoroacetone.

Kenis S, D'hooghe M, Verniest G, Nguyen VD, Thi TA, Nguyen TV, De Kimpe N. Kenis S, et al. Org Biomol Chem. 2011 Oct 21;9(20):7217-23. doi: 10.1039/c1ob05813d. Epub 2011 Aug 26. Org Biomol Chem. 2011. PMID: 21874207

2

New synthesis of propargylic amines from 2-(bromomethyl)aziridines. Intermediacy of 3-bromoazetidinium salts.

D'hooghe M, Van Brabandt W, De Kimpe N. D'hooghe M, et al. J Org Chem. 2004 Apr 16;69(8):2703-10. doi: 10.1021/jo035759i. J Org Chem. 2004. PMID: 15074916

3

A novel entry toward 2-imino-1,3-thiazolidines and 2-imino-1,3-thiazolines by ring transformation of 2-(thiocyanomethyl)aziridines.

D'Hooghe M, Waterinckx A, De Kimpe N. D'Hooghe M, et al. J Org Chem. 2005 Jan 7;70(1):227-32. doi: 10.1021/jo048486f. J Org Chem. 2005. PMID: 15624926

4

Regio- and stereospecific ring opening of 1,1-dialkyl-2-(aryloxymethyl)aziridinium salts by bromide.

D'hooghe M, Van Speybroeck V, Waroquier M, De Kimpe N. D'hooghe M, et al. Chem Commun (Camb). 2006 Apr 14;(14):1554-6. doi: 10.1039/b518298k. Epub 2006 Mar 2. Chem Commun (Camb). 2006. PMID: 16575458

5

Synthesis of 1-arylmethyl-2-(cyanomethyl)aziridines and their ring transformation into methyl N-(2-cyanocyclopropyl)benzimidates.

D'hooghe M, Mangelinckx S, Persyn E, Van Brabandt W, De Kimpe N. D'hooghe M, et al. J Org Chem. 2006 May 26;71(11):4232-6. doi: 10.1021/jo060425p. J Org Chem. 2006. PMID: 16709066

6

Novel synthesis of cis-3,5-disubstituted morpholine derivatives.

D'hooghe M, Vanlangendonck T, Törnroos KW, De Kimpe N. D'hooghe M, et al. J Org Chem. 2006 Jun 9;71(12):4678-81. doi: 10.1021/jo060313y. J Org Chem. 2006. PMID: 16749806

7

Asymmetric synthesis of 1-(2- and 3-haloalkyl)azetidin-2-ones as precursors for novel piperazine, morpholine, and 1,4-diazepane annulated beta-lactams.

Van Brabandt W, Vanwalleghem M, D'hooghe M, De Kimpe N. Van Brabandt W, et al. J Org Chem. 2006 Sep 1;71(18):7083-6. doi: 10.1021/jo0608319. J Org Chem. 2006. PMID: 16930070

8

Highly unusual conversion of 1-alkyl-2-(bromomethyl)aziridines into 1-alkyl-2-(N-alkyl-N-ethylaminomethyl)aziridines using methyllithium.

D'hooghe M, De Kimpe N. D'hooghe M, et al. Chem Commun (Camb). 2007 Mar 28;(12):1275-7. doi: 10.1039/b616606g. Epub 2007 Jan 15. Chem Commun (Camb). 2007. PMID: 17356781

9

Synthesis and reactivity of C-heteroatom-substituted aziridines.

Singh GS, D'hooghe M, De Kimpe N. Singh GS, et al. Chem Rev. 2007 May;107(5):2080-135. doi: 10.1021/cr0680033. Chem Rev. 2007. PMID: 17488062 Review. No abstract available.

10

Novel synthesis of 3,4-diaminobutanenitriles and 4-amino-2-butenenitriles from 2-(cyanomethyl)aziridines through intermediate aziridinium salts: an experimental and theoretical approach.

D'hooghe M, Van Speybroeck V, Van Nieuwenhove A, Waroquier M, De Kimpe N. D'hooghe M, et al. J Org Chem. 2007 Jun 22;72(13):4733-40. doi: 10.1021/jo0704210. Epub 2007 May 26. J Org Chem. 2007. PMID: 17530805

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