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ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo.
Burgess BL, Parkinson PF, Racke MM, Hirsch-Reinshagen V, Fan J, Wong C, Stukas S, Theroux L, Chan JY, Donkin J, Wilkinson A, Balik D, Christie B, Poirier J, Lütjohann D, Demattos RB, Wellington CL. Burgess BL, et al. Among authors: stukas s. J Lipid Res. 2008 Jun;49(6):1254-67. doi: 10.1194/jlr.M700481-JLR200. Epub 2008 Feb 26. J Lipid Res. 2008. PMID: 18314463 Free article.
ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice.
Donkin JJ, Stukas S, Hirsch-Reinshagen V, Namjoshi D, Wilkinson A, May S, Chan J, Fan J, Collins J, Wellington CL. Donkin JJ, et al. Among authors: stukas s. J Biol Chem. 2010 Oct 29;285(44):34144-54. doi: 10.1074/jbc.M110.108100. Epub 2010 Aug 25. J Biol Chem. 2010. PMID: 20739291 Free PMC article.
ABCA1 influences neuroinflammation and neuronal death.
Karasinska JM, de Haan W, Franciosi S, Ruddle P, Fan J, Kruit JK, Stukas S, Lütjohann D, Gutmann DH, Wellington CL, Hayden MR. Karasinska JM, et al. Among authors: stukas s. Neurobiol Dis. 2013 Jun;54:445-55. doi: 10.1016/j.nbd.2013.01.018. Epub 2013 Jan 30. Neurobiol Dis. 2013. PMID: 23376685
LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice.
Stukas S, Freeman L, Lee M, Wilkinson A, Ossoli A, Vaisman B, Demosky S, Chan J, Hirsch-Reinshagen V, Remaley AT, Wellington CL. Stukas S, et al. J Lipid Res. 2014 Aug;55(8):1721-9. doi: 10.1194/jlr.M049940. Epub 2014 Jun 20. J Lipid Res. 2014. PMID: 24950691 Free PMC article.
46 results