Van Raamsdonk JM - Search Results

1

FUdR causes a twofold increase in the lifespan of the mitochondrial mutant gas-1.

Van Raamsdonk JM, Hekimi S. Van Raamsdonk JM, et al. Mech Ageing Dev. 2011 Oct;132(10):519-21. doi: 10.1016/j.mad.2011.08.006. Epub 2011 Aug 27. Mech Ageing Dev. 2011. PMID: 21893079 Free PMC article.

2

Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans.

Van Raamsdonk JM, Hekimi S. Van Raamsdonk JM, et al. PLoS Genet. 2009 Feb;5(2):e1000361. doi: 10.1371/journal.pgen.1000361. Epub 2009 Feb 6. PLoS Genet. 2009. PMID: 19197346 Free PMC article.

3

Decreased energy metabolism extends life span in Caenorhabditis elegans without reducing oxidative damage.

Van Raamsdonk JM, Meng Y, Camp D, Yang W, Jia X, Bénard C, Hekimi S. Van Raamsdonk JM, et al. Genetics. 2010 Jun;185(2):559-71. doi: 10.1534/genetics.110.115378. Epub 2010 Apr 9. Genetics. 2010. PMID: 20382831 Free PMC article.

4

Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship?

Van Raamsdonk JM, Hekimi S. Van Raamsdonk JM, et al. Antioxid Redox Signal. 2010 Dec 15;13(12):1911-53. doi: 10.1089/ars.2010.3215. Epub 2010 Sep 13. Antioxid Redox Signal. 2010. PMID: 20568954 Review.

5

Superoxide dismutase is dispensable for normal animal lifespan.

Van Raamsdonk JM, Hekimi S. Van Raamsdonk JM, et al. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5785-90. doi: 10.1073/pnas.1116158109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451939 Free PMC article.

6

Mitochondrial and cytoplasmic ROS have opposing effects on lifespan.

Schaar CE, Dues DJ, Spielbauer KK, Machiela E, Cooper JF, Senchuk M, Hekimi S, Van Raamsdonk JM. Schaar CE, et al. Among authors: van raamsdonk jm. PLoS Genet. 2015 Feb 11;11(2):e1004972. doi: 10.1371/journal.pgen.1004972. eCollection 2015 Feb. PLoS Genet. 2015. PMID: 25671321 Free PMC article.

7

Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways.

Wu Z, Senchuk MM, Dues DJ, Johnson BK, Cooper JF, Lew L, Machiela E, Schaar CE, DeJonge H, Blackwell TK, Van Raamsdonk JM. Wu Z, et al. Among authors: van raamsdonk jm. BMC Biol. 2018 Dec 18;16(1):147. doi: 10.1186/s12915-018-0615-3. BMC Biol. 2018. PMID: 30563508 Free PMC article.

8

Compounds that extend longevity are protective in neurodegenerative diseases and provide a novel treatment strategy for these devastating disorders.

Soo SK, Rudich PD, Traa A, Harris-Gauthier N, Shields HJ, Van Raamsdonk JM. Soo SK, et al. Among authors: van raamsdonk jm. Mech Ageing Dev. 2020 Sep;190:111297. doi: 10.1016/j.mad.2020.111297. Epub 2020 Jun 28. Mech Ageing Dev. 2020. PMID: 32610099 Free PMC article. Review.

9

Mild mitochondrial impairment enhances innate immunity and longevity through ATFS-1 and p38 signaling.

Campos JC, Wu Z, Rudich PD, Soo SK, Mistry M, Ferreira JC, Blackwell TK, Van Raamsdonk JM. Campos JC, et al. Among authors: van raamsdonk jm. EMBO Rep. 2021 Dec 6;22(12):e52964. doi: 10.15252/embr.202152964. Epub 2021 Oct 7. EMBO Rep. 2021. PMID: 34617666 Free PMC article.

10

Mitochondrial thioredoxin system is required for enhanced stress resistance and extended longevity in long-lived mitochondrial mutants.

Harris-Gauthier N, Traa A, AlOkda A, Moldakozhayev A, Anglas U, Soo SK, Van Raamsdonk JM. Harris-Gauthier N, et al. Among authors: van raamsdonk jm. Redox Biol. 2022 Jul;53:102335. doi: 10.1016/j.redox.2022.102335. Epub 2022 May 13. Redox Biol. 2022. PMID: 35598379 Free PMC article.

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