Steptoe RJ - Search Results

1

Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation.

O'Sullivan BJ, Pai S, Street S, An X, MacDonald KP, Wong M, Strutton G, Gerondakis S, Steptoe RJ, de St Groth BF, Hill GR, Thomas R. O'Sullivan BJ, et al. Among authors: steptoe rj. J Immunol. 2011 Oct 15;187(8):4018-30. doi: 10.4049/jimmunol.1101727. Epub 2011 Sep 7. J Immunol. 2011. PMID: 21900177

2

Antigen-specific suppression of inflammatory arthritis using liposomes.

Capini C, Jaturanpinyo M, Chang HI, Mutalik S, McNally A, Street S, Steptoe R, O'Sullivan B, Davies N, Thomas R. Capini C, et al. J Immunol. 2009 Mar 15;182(6):3556-65. doi: 10.4049/jimmunol.0802972. J Immunol. 2009. PMID: 19265134

3

IL-1 beta breaks tolerance through expansion of CD25+ effector T cells.

O'Sullivan BJ, Thomas HE, Pai S, Santamaria P, Iwakura Y, Steptoe RJ, Kay TW, Thomas R. O'Sullivan BJ, et al. Among authors: steptoe rj. J Immunol. 2006 Jun 15;176(12):7278-87. doi: 10.4049/jimmunol.176.12.7278. J Immunol. 2006. PMID: 16751371

4

Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection.

Doan T, McNally A, Thomas R, Steptoe RJ. Doan T, et al. Among authors: steptoe rj. Immunol Cell Biol. 2009 Nov-Dec;87(8):615-22. doi: 10.1038/icb.2009.46. Epub 2009 Jul 7. Immunol Cell Biol. 2009. PMID: 19581919

5

Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy.

Bertin-Maghit S, Pang D, O'Sullivan B, Best S, Duggan E, Paul S, Thomas H, Kay TW, Harrison LC, Steptoe R, Thomas R. Bertin-Maghit S, et al. Diabetes. 2011 Jan;60(1):248-57. doi: 10.2337/db10-0104. Epub 2010 Oct 27. Diabetes. 2011. PMID: 20980463 Free PMC article.

6

Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses.

Kenna TJ, Thomas R, Steptoe RJ. Kenna TJ, et al. Among authors: steptoe rj. Blood. 2008 Feb 15;111(4):2091-100. doi: 10.1182/blood-2007-07-103200. Epub 2007 Nov 14. Blood. 2008. PMID: 18003887 Free article.

7

Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function.

Kenna TJ, Waldie T, McNally A, Thomson M, Yagita H, Thomas R, Steptoe RJ. Kenna TJ, et al. Among authors: steptoe rj. J Immunol. 2010 Jan 15;184(2):598-606. doi: 10.4049/jimmunol.0900032. Epub 2009 Dec 7. J Immunol. 2010. PMID: 19995901

8

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis.

McNally A, Hill GR, Sparwasser T, Thomas R, Steptoe RJ. McNally A, et al. Among authors: steptoe rj. Proc Natl Acad Sci U S A. 2011 May 3;108(18):7529-34. doi: 10.1073/pnas.1103782108. Epub 2011 Apr 18. Proc Natl Acad Sci U S A. 2011. PMID: 21502514 Free PMC article.

9

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy.

Coleman MA, Bridge JA, Lane SW, Dixon CM, Hill GR, Wells JW, Thomas R, Steptoe RJ. Coleman MA, et al. Among authors: steptoe rj. Blood. 2013 Feb 7;121(6):1049-58. doi: 10.1182/blood-2012-06-434100. Epub 2012 Dec 11. Blood. 2013. PMID: 23233664 Free article.

10

Immunogenic, but not steady-state, antigen presentation permits regulatory T-cells to control CD8+ T-cell effector differentiation by IL-2 modulation.

McNally A, McNally M, Galea R, Thomas R, Steptoe RJ. McNally A, et al. Among authors: steptoe rj. PLoS One. 2014 Jan 13;9(1):e85455. doi: 10.1371/journal.pone.0085455. eCollection 2014. PLoS One. 2014. PMID: 24454872 Free PMC article.

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