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KRN5500, a spicamycin derivative, exerts anti-myeloma effects through impairing both myeloma cells and osteoclasts.
Miki H, Ozaki S, Nakamura S, Oda A, Amou H, Ikegame A, Watanabe K, Hiasa M, Cui Q, Harada T, Fujii S, Nakano A, Kagawa K, Takeuchi K, Yata K, Sakai A, Abe M, Matsumoto T. Miki H, et al. Among authors: yata k. Br J Haematol. 2011 Nov;155(3):328-39. doi: 10.1111/j.1365-2141.2011.08844.x. Epub 2011 Sep 9. Br J Haematol. 2011. PMID: 21902681 Free article.
Targeting myeloma-osteoclast interaction with Vγ9Vδ2 T cells.
Cui Q, Shibata H, Oda A, Amou H, Nakano A, Yata K, Hiasa M, Watanabe K, Nakamura S, Miki H, Harada T, Fujii S, Kagawa K, Takeuchi K, Ozaki S, Matsumoto T, Abe M. Cui Q, et al. Among authors: yata k. Int J Hematol. 2011 Jul;94(1):63-70. doi: 10.1007/s12185-011-0885-9. Epub 2011 Jun 23. Int J Hematol. 2011. PMID: 21698356
GM-CSF and IL-4 induce dendritic cell differentiation and disrupt osteoclastogenesis through M-CSF receptor shedding by up-regulation of TNF-alpha converting enzyme (TACE).
Hiasa M, Abe M, Nakano A, Oda A, Amou H, Kido S, Takeuchi K, Kagawa K, Yata K, Hashimoto T, Ozaki S, Asaoka K, Tanaka E, Moriyama K, Matsumoto T. Hiasa M, et al. Among authors: yata k. Blood. 2009 Nov 12;114(20):4517-26. doi: 10.1182/blood-2009-04-215020. Epub 2009 Sep 17. Blood. 2009. PMID: 19762488 Free article.
117 results