Le Quement ST - Search Results

1

Solid-phase synthesis of smac peptidomimetics incorporating triazoloprolines and biarylalanines.

Le Quement ST, Ishoey M, Petersen MT, Thastrup J, Hagel G, Nielsen TE. Le Quement ST, et al. ACS Comb Sci. 2011 Nov 14;13(6):667-75. doi: 10.1021/co200078u. Epub 2011 Sep 28. ACS Comb Sci. 2011. PMID: 21905744

2

Solid-phase synthesis of aryl-substituted thienoindolizines: sequential Pictet-Spengler, bromination and Suzuki cross-coupling reactions of thiophenes.

Le Quement ST, Nielsen TE, Meldal M. Le Quement ST, et al. J Comb Chem. 2008 May-Jun;10(3):447-55. doi: 10.1021/cc700199n. Epub 2008 Apr 4. J Comb Chem. 2008. PMID: 18386932

3

Divergent pathway for the solid-phase conversion of aromatic acetylenes to carboxylic acids, alpha-ketocarboxylic acids, and methyl ketones.

Le Quement ST, Nielsen TE, Meldal M. Le Quement ST, et al. J Comb Chem. 2008 Jul-Aug;10(4):546-56. doi: 10.1021/cc8000037. Epub 2008 Jun 28. J Comb Chem. 2008. PMID: 18588350

4

Scaffold diversity through intramolecular cascade reactions of solid-supported cyclic N-acyliminium intermediates.

Le Quement ST, Nielsen TE, Meldal M. Le Quement ST, et al. J Comb Chem. 2007 Nov-Dec;9(6):1060-72. doi: 10.1021/cc700097k. Epub 2007 Nov 12. J Comb Chem. 2007. PMID: 17994787

5

N-acyliminium intermediates in solid-phase synthesis.

Le Quement ST, Petersen R, Meldal M, Nielsen TE. Le Quement ST, et al. Biopolymers. 2010;94(2):242-56. doi: 10.1002/bip.21358. Biopolymers. 2010. PMID: 20225296 Review.

6

Build/couple/pair strategy combining the Petasis 3-component reaction with Ru-catalyzed ring-closing metathesis and isomerization.

Ascic E, Le Quement ST, Ishoey M, Daugaard M, Nielsen TE. Ascic E, et al. Among authors: le quement st. ACS Comb Sci. 2012 Apr 9;14(4):253-7. doi: 10.1021/co300001e. Epub 2012 Mar 23. ACS Comb Sci. 2012. PMID: 22356899

7

Synthesis of a natural product-like compound collection through oxidative cleavage and cyclization of linear peptides.

Petersen R, Le Quement ST, Nielsen TE. Petersen R, et al. Among authors: le quement st. Angew Chem Int Ed Engl. 2014 Oct 27;53(44):11778-82. doi: 10.1002/anie.201405747. Epub 2014 Sep 11. Angew Chem Int Ed Engl. 2014. PMID: 25214457

8

Combining the Petasis 3-component reaction with multiple modes of cyclization: a build/couple/pair strategy for the synthesis of densely functionalized small molecules.

Flagstad T, Hansen MR, Le Quement ST, Givskov M, Nielsen TE. Flagstad T, et al. Among authors: le quement st. ACS Comb Sci. 2015 Jan 12;17(1):19-23. doi: 10.1021/co500091f. Epub 2014 Dec 17. ACS Comb Sci. 2015. PMID: 25469710

9

Solid-phase synthesis of bicyclic dipeptide mimetics by intramolecular cyclization of alcohols, thiols, amines, and amides with N-acyliminium intermediates.

Nielsen TE, Le Quement S, Meldal M. Nielsen TE, et al. Org Lett. 2005 Aug 18;7(17):3601-4. doi: 10.1021/ol050871j. Org Lett. 2005. PMID: 16092829

10

Solid-phase synthesis of carboxylic and oxamic acids via OsO4/NaIO4/HMTA-mediated oxidative cleavage of acetylenic peptides.

Nielsen TE, Le Quement ST, Meldal M. Nielsen TE, et al. Among authors: le quement st. Org Lett. 2007 Jun 21;9(13):2469-72. doi: 10.1021/ol070693p. Epub 2007 May 23. Org Lett. 2007. PMID: 17518476

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