Conn PM - Search Results

1

Pharmacological chaperones for misfolded gonadotropin-releasing hormone receptors.

Conn PM, Ulloa-Aguirre A. Conn PM, et al. Adv Pharmacol. 2011;62:109-41. doi: 10.1016/B978-0-12-385952-5.00008-7. Adv Pharmacol. 2011. PMID: 21907908 Free PMC article. Review.

2

Dominant-negative action of disease-causing gonadotropin-releasing hormone receptor (GnRHR) mutants: a trait that potentially coevolved with decreased plasma membrane expression of GnRHR in humans.

Leaños-Miranda A, Ulloa-Aguirre A, Ji TH, Janovick JA, Conn PM. Leaños-Miranda A, et al. Among authors: conn pm. J Clin Endocrinol Metab. 2003 Jul;88(7):3360-7. doi: 10.1210/jc.2003-030084. J Clin Endocrinol Metab. 2003. PMID: 12843188

3

Evolved regulation of gonadotropin-releasing hormone receptor cell surface expression.

Janovick JA, Ulloa-Aguirre A, Conn PM. Janovick JA, et al. Among authors: conn pm. Endocrine. 2003 Dec;22(3):317-27. doi: 10.1385/ENDO:22:3:317. Endocrine. 2003. PMID: 14709805

4

Pharmacologic rescue of conformationally-defective proteins: implications for the treatment of human disease.

Ulloa-Aguirre A, Janovick JA, Brothers SP, Conn PM. Ulloa-Aguirre A, et al. Among authors: conn pm. Traffic. 2004 Nov;5(11):821-37. doi: 10.1111/j.1600-0854.2004.00232.x. Traffic. 2004. PMID: 15479448 Free article. Review.

5

G-protein-coupled receptor trafficking: understanding the chemical basis of health and disease.

Ulloa-Aguirre A, Janovick JA, Miranda AL, Conn PM. Ulloa-Aguirre A, et al. Among authors: conn pm. ACS Chem Biol. 2006 Nov 21;1(10):631-8. doi: 10.1021/cb600360h. ACS Chem Biol. 2006. PMID: 17168568 Review.

6

Trafficking of G-protein-coupled receptors to the plasma membrane: insights for pharmacoperone drugs.

Conn PM, Ulloa-Aguirre A. Conn PM, et al. Trends Endocrinol Metab. 2010 Mar;21(3):190-7. doi: 10.1016/j.tem.2009.11.003. Epub 2009 Dec 11. Trends Endocrinol Metab. 2010. PMID: 20005736 Free PMC article. Review.

7

Pharmacological chaperones correct misfolded GPCRs and rescue function: protein trafficking as a therapeutic target.

Maya-Núñez G, Ulloa-Aguirre A, Janovick JA, Conn PM. Maya-Núñez G, et al. Among authors: conn pm. Subcell Biochem. 2012;63:263-89. doi: 10.1007/978-94-007-4765-4_14. Subcell Biochem. 2012. PMID: 23161143 Review.

8

Mutations in G protein-coupled receptors that impact receptor trafficking and reproductive function.

Ulloa-Aguirre A, Zariñán T, Dias JA, Conn PM. Ulloa-Aguirre A, et al. Among authors: conn pm. Mol Cell Endocrinol. 2014 Jan 25;382(1):411-423. doi: 10.1016/j.mce.2013.06.024. Epub 2013 Jun 24. Mol Cell Endocrinol. 2014. PMID: 23806559 Free PMC article. Review.

9

The third intracellular loop of the rat gonadotropin-releasing hormone receptor couples the receptor to Gs- and G(q/11)-mediated signal transduction pathways: evidence from loop fragment transfection in GGH3 cells.

Ulloa-Aguirre A, Stanislaus D, Arora V, Väänänen J, Brothers S, Janovick JA, Conn PM. Ulloa-Aguirre A, et al. Among authors: conn pm. Endocrinology. 1998 May;139(5):2472-8. doi: 10.1210/endo.139.5.6022. Endocrinology. 1998. PMID: 9564860

10

Misrouted cell surface receptors as a novel disease aetiology and potential therapeutic target: the case of hypogonadotropic hypogonadism due to gonadotropin-releasing hormone resistance.

Ulloa-Aguirre A, Janovick JA, Leaños-Miranda A, Conn PM. Ulloa-Aguirre A, et al. Among authors: conn pm. Expert Opin Ther Targets. 2003 Apr;7(2):175-85. doi: 10.1517/14728222.7.2.175. Expert Opin Ther Targets. 2003. PMID: 12667096 Review.

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