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Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL.
Mali RS, Ramdas B, Ma P, Shi J, Munugalavadla V, Sims E, Wei L, Vemula S, Nabinger SC, Goodwin CB, Chan RJ, Traina F, Visconte V, Tiu RV, Lewis TA, Stern AM, Wen Q, Crispino JD, Boswell HS, Kapur R. Mali RS, et al. Among authors: tiu rv. Cancer Cell. 2011 Sep 13;20(3):357-69. doi: 10.1016/j.ccr.2011.07.016. Cancer Cell. 2011. PMID: 21907926 Free PMC article.
Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis.
Chatterjee A, Ghosh J, Ramdas B, Mali RS, Martin H, Kobayashi M, Vemula S, Canela VH, Waskow ER, Visconte V, Tiu RV, Smith CC, Shah N, Bunting KD, Boswell HS, Liu Y, Chan RJ, Kapur R. Chatterjee A, et al. Among authors: tiu rv. Cell Rep. 2014 Nov 20;9(4):1333-48. doi: 10.1016/j.celrep.2014.10.039. Epub 2014 Nov 13. Cell Rep. 2014. PMID: 25456130 Free PMC article.
Pak and Rac GTPases promote oncogenic KIT-induced neoplasms.
Martin H, Mali RS, Ma P, Chatterjee A, Ramdas B, Sims E, Munugalavadla V, Ghosh J, Mattingly RR, Visconte V, Tiu RV, Vlaar CP, Dharmawardhane S, Kapur R. Martin H, et al. Among authors: tiu rv. J Clin Invest. 2013 Oct;123(10):4449-63. doi: 10.1172/JCI67509. Epub 2013 Sep 16. J Clin Invest. 2013. PMID: 24091327 Free PMC article.
Clofarabine for myelodysplastic syndromes.
Tiu RV, Traina F, Sekeres MA. Tiu RV, et al. Expert Opin Investig Drugs. 2011 Jul;20(7):1005-14. doi: 10.1517/13543784.2011.585967. Epub 2011 May 19. Expert Opin Investig Drugs. 2011. PMID: 21591997 Review.
Updates in cytogenetics and molecular markers in MDS.
Tiu RV, Visconte V, Traina F, Schwandt A, Maciejewski JP. Tiu RV, et al. Curr Hematol Malig Rep. 2011 Jun;6(2):126-35. doi: 10.1007/s11899-011-0081-2. Curr Hematol Malig Rep. 2011. PMID: 21340513 Review.
Familial systemic mastocytosis with germline KIT K509I mutation is sensitive to treatment with imatinib, dasatinib and PKC412.
de Melo Campos P, Machado-Neto JA, Scopim-Ribeiro R, Visconte V, Tabarroki A, Duarte AS, Barra FF, Vassalo J, Rogers HJ, Lorand-Metze I, Tiu RV, Costa FF, Olalla Saad ST, Traina F. de Melo Campos P, et al. Among authors: tiu rv. Leuk Res. 2014 Oct;38(10):1245-51. doi: 10.1016/j.leukres.2014.07.010. Epub 2014 Aug 1. Leuk Res. 2014. PMID: 25139846 Free article.
Impact of allogeneic hematopoietic cell transplant in patients with myeloid neoplasms carrying spliceosomal mutations.
Hamilton BK, Visconte V, Jia X, Tabarroki A, Makishima H, Hasrouni E, Abounader D, Kalaycio M, Sekeres MA, Sobecks R, Duong Liu H, Bolwell B, Maciejewski JP, Copelan E, Tiu RV. Hamilton BK, et al. Among authors: tiu rv. Am J Hematol. 2016 Jun;91(4):406-9. doi: 10.1002/ajh.24306. Epub 2016 Mar 14. Am J Hematol. 2016. PMID: 26799334 Free article.
123 results