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432 results

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Page 1
Nuclear phosphoinositides and their roles in cell biology and disease.
Martelli AM, Ognibene A, Buontempo F, Fini M, Bressanin D, Goto K, McCubrey JA, Cocco L, Evangelisti C. Martelli AM, et al. Among authors: mccubrey ja. Crit Rev Biochem Mol Biol. 2011 Oct;46(5):436-57. doi: 10.3109/10409238.2011.609530. Epub 2011 Sep 14. Crit Rev Biochem Mol Biol. 2011. PMID: 21913876
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance.
McCubrey JA, Steelman LS, Chappell WH, Abrams SL, Wong EW, Chang F, Lehmann B, Terrian DM, Milella M, Tafuri A, Stivala F, Libra M, Basecke J, Evangelisti C, Martelli AM, Franklin RA. McCubrey JA, et al. Biochim Biophys Acta. 2007 Aug;1773(8):1263-84. doi: 10.1016/j.bbamcr.2006.10.001. Epub 2006 Oct 7. Biochim Biophys Acta. 2007. PMID: 17126425 Free PMC article. Review.
Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts.
Tazzari PL, Cappellini A, Ricci F, Evangelisti C, Papa V, Grafone T, Martinelli G, Conte R, Cocco L, McCubrey JA, Martelli AM. Tazzari PL, et al. Among authors: mccubrey ja. Leukemia. 2007 Mar;21(3):427-38. doi: 10.1038/sj.leu.2404523. Epub 2007 Jan 11. Leukemia. 2007. PMID: 17215852
Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance.
McCubrey JA, Steelman LS, Franklin RA, Abrams SL, Chappell WH, Wong EW, Lehmann BD, Terrian DM, Basecke J, Stivala F, Libra M, Evangelisti C, Martelli AM. McCubrey JA, et al. Adv Enzyme Regul. 2007;47:64-103. doi: 10.1016/j.advenzreg.2006.12.013. Epub 2007 Mar 26. Adv Enzyme Regul. 2007. PMID: 17382374 Free PMC article. No abstract available.
The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism.
Chiarini F, Del Sole M, Mongiorgi S, Gaboardi GC, Cappellini A, Mantovani I, Follo MY, McCubrey JA, Martelli AM. Chiarini F, et al. Among authors: mccubrey ja. Leukemia. 2008 Jun;22(6):1106-16. doi: 10.1038/leu.2008.79. Epub 2008 Apr 3. Leukemia. 2008. PMID: 18385752
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia.
Falà F, Blalock WL, Tazzari PL, Cappellini A, Chiarini F, Martinelli G, Tafuri A, McCubrey JA, Cocco L, Martelli AM. Falà F, et al. Among authors: mccubrey ja. Mol Pharmacol. 2008 Sep;74(3):884-95. doi: 10.1124/mol.108.047639. Epub 2008 Jun 24. Mol Pharmacol. 2008. PMID: 18577685 Free PMC article.
Targeting prostate cancer based on signal transduction and cell cycle pathways.
Lee JT, Lehmann BD, Terrian DM, Chappell WH, Stivala F, Libra M, Martelli AM, Steelman LS, McCubrey JA. Lee JT, et al. Among authors: mccubrey ja. Cell Cycle. 2008 Jun 15;7(12):1745-62. doi: 10.4161/cc.7.12.6166. Epub 2008 Jun 16. Cell Cycle. 2008. PMID: 18594202 Free PMC article. Review.
432 results