Saayman S - Search Results

1

The biogenesis and characterization of mammalian microRNAs of mirtron origin.

Sibley CR, Seow Y, Saayman S, Dijkstra KK, El Andaloussi S, Weinberg MS, Wood MJ. Sibley CR, et al. Among authors: saayman s. Nucleic Acids Res. 2012 Jan;40(1):438-48. doi: 10.1093/nar/gkr722. Epub 2011 Sep 13. Nucleic Acids Res. 2012. PMID: 21914725 Free PMC article.

2

Deriving four functional anti-HIV siRNAs from a single Pol III-generated transcript comprising two adjacent long hairpin RNA precursors.

Saayman S, Arbuthnot P, Weinberg MS. Saayman S, et al. Nucleic Acids Res. 2010 Oct;38(19):6652-63. doi: 10.1093/nar/gkq460. Epub 2010 Jun 4. Nucleic Acids Res. 2010. PMID: 20525791 Free PMC article.

3

Effective Pol III-expressed long hairpin RNAs targeted to multiple unique sites of HIV-1.

Saayman SM, Arbuthnot P, Weinberg MS. Saayman SM, et al. Methods Mol Biol. 2010;629:159-74. doi: 10.1007/978-1-60761-657-3_11. Methods Mol Biol. 2010. PMID: 20387149

4

The inhibitory efficacy of RNA POL III-expressed long hairpin RNAs targeted to untranslated regions of the HIV-1 5' long terminal repeat.

Barichievy S, Saayman S, von Eije KJ, Morris KV, Arbuthnot P, Weinberg MS. Barichievy S, et al. Among authors: saayman s. Oligonucleotides. 2007 Winter;17(4):419-31. doi: 10.1089/oli.2007.0095. Oligonucleotides. 2007. PMID: 17896874

5

The efficacy of generating three independent anti-HIV-1 siRNAs from a single U6 RNA Pol III-expressed long hairpin RNA.

Saayman S, Barichievy S, Capovilla A, Morris KV, Arbuthnot P, Weinberg MS. Saayman S, et al. PLoS One. 2008 Jul 2;3(7):e2602. doi: 10.1371/journal.pone.0002602. PLoS One. 2008. PMID: 18596982 Free PMC article.

6

RNA interference-based gene expression strategies aimed at sustained therapeutic inhibition of HIV.

Barichievy S, Saayman S, Arbuthnot P, Weinberg MS. Barichievy S, et al. Among authors: saayman s. Curr Top Med Chem. 2009;9(12):1065-78. doi: 10.2174/156802609789630901. Curr Top Med Chem. 2009. PMID: 19860707 Review.

7

HIV Latency and the noncoding RNA therapeutic landscape.

Saayman S, Roberts TC, Morris KV, Weinberg MS. Saayman S, et al. Adv Exp Med Biol. 2015;848:169-89. doi: 10.1007/978-1-4939-2432-5_9. Adv Exp Med Biol. 2015. PMID: 25757621 Review.

8

The therapeutic application of CRISPR/Cas9 technologies for HIV.

Saayman S, Ali SA, Morris KV, Weinberg MS. Saayman S, et al. Expert Opin Biol Ther. 2015 Jun;15(6):819-30. doi: 10.1517/14712598.2015.1036736. Epub 2015 Apr 12. Expert Opin Biol Ther. 2015. PMID: 25865334 Free PMC article. Review.

9

Potent and Targeted Activation of Latent HIV-1 Using the CRISPR/dCas9 Activator Complex.

Saayman SM, Lazar DC, Scott TA, Hart JR, Takahashi M, Burnett JC, Planelles V, Morris KV, Weinberg MS. Saayman SM, et al. Mol Ther. 2016 Mar;24(3):488-98. doi: 10.1038/mt.2015.202. Epub 2015 Nov 19. Mol Ther. 2016. PMID: 26581162 Free PMC article.

10

Receptor-targeted aptamer-siRNA conjugate-directed transcriptional regulation of HIV-1.

Zhou J, Lazar D, Li H, Xia X, Satheesan S, Charlins P, O'Mealy D, Akkina R, Saayman S, Weinberg MS, Rossi JJ, Morris KV. Zhou J, et al. Among authors: saayman s. Theranostics. 2018 Feb 7;8(6):1575-1590. doi: 10.7150/thno.23085. eCollection 2018. Theranostics. 2018. PMID: 29556342 Free PMC article.

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