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Page 1
Polyalkoxybenzenes from plants. 5. Parsley seed extract in synthesis of azapodophyllotoxins featuring strong tubulin destabilizing activity in the sea urchin embryo and cell culture assays.
Semenova MN, Kiselyov AS, Tsyganov DV, Konyushkin LD, Firgang SI, Semenov RV, Malyshev OR, Raihstat MM, Fuchs F, Stielow A, Lantow M, Philchenkov AA, Zavelevich MP, Zefirov NS, Kuznetsov SA, Semenov VV. Semenova MN, et al. Among authors: raihstat mm. J Med Chem. 2011 Oct 27;54(20):7138-49. doi: 10.1021/jm200737s. Epub 2011 Sep 29. J Med Chem. 2011. PMID: 21916509
Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays.
Kiselyov AS, Semenova MN, Chernyshova NB, Leitao A, Samet AV, Kislyi KA, Raihstat MM, Oprea T, Lemcke H, Lantow M, Weiss DG, Ikizalp NN, Kuznetsov SA, Semenov VV. Kiselyov AS, et al. Among authors: raihstat mm. Eur J Med Chem. 2010 May;45(5):1683-97. doi: 10.1016/j.ejmech.2009.12.072. Epub 2010 Jan 14. Eur J Med Chem. 2010. PMID: 20110137
Synthesis of antimitotic polyalkoxyphenyl derivatives of combretastatin using plant allylpolyalkoxybenzenes.
Semenov VV, Kiselyov AS, Titov IY, Sagamanova IK, Ikizalp NN, Chernysheva NB, Tsyganov DV, Konyushkin LD, Firgang SI, Semenov RV, Karmanova IB, Raihstat MM, Semenova MN. Semenov VV, et al. Among authors: raihstat mm. J Nat Prod. 2010 Nov 29;73(11):1796-802. doi: 10.1021/np1004278. Epub 2010 Nov 4. J Nat Prod. 2010. PMID: 21049975 No abstract available.
Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines.
Demchuk DV, Samet AV, Chernysheva NB, Ushkarov VI, Stashina GA, Konyushkin LD, Raihstat MM, Firgang SI, Philchenkov AA, Zavelevich MP, Kuiava LM, Chekhun VF, Blokhin DY, Kiselyov AS, Semenova MN, Semenov VV. Demchuk DV, et al. Among authors: raihstat mm. Bioorg Med Chem. 2014 Jan 15;22(2):738-55. doi: 10.1016/j.bmc.2013.12.015. Epub 2013 Dec 12. Bioorg Med Chem. 2014. PMID: 24387982
Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity.
Semenov VV, Tsyganov DV, Semenova MN, Chuprov-Netochin RN, Raihstat MM, Konyushkin LD, Volynchuk PB, Marusich EI, Nazarenko VV, Leonov SV, Kiselyov AS. Semenov VV, et al. Among authors: raihstat mm. J Nat Prod. 2016 May 27;79(5):1429-38. doi: 10.1021/acs.jnatprod.6b00173. Epub 2016 Apr 21. J Nat Prod. 2016. PMID: 27100701
Sea Urchin Embryo Model As a Reliable in Vivo Phenotypic Screen to Characterize Selective Antimitotic Molecules. Comparative evaluation of Combretapyrazoles, -isoxazoles, -1,2,3-triazoles, and -pyrroles as Tubulin-Binding Agents.
Semenova MN, Demchuk DV, Tsyganov DV, Chernysheva NB, Samet AV, Silyanova EA, Kislyi VP, Maksimenko AS, Varakutin AE, Konyushkin LD, Raihstat MM, Kiselyov AS, Semenov VV. Semenova MN, et al. Among authors: raihstat mm. ACS Comb Sci. 2018 Dec 10;20(12):700-721. doi: 10.1021/acscombsci.8b00113. Epub 2018 Nov 29. ACS Comb Sci. 2018. PMID: 30452225