Egli M - Search Results

1

Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotides.

Egli M, Pallan PS, Allerson CR, Prakash TP, Berdeja A, Yu J, Lee S, Watt A, Gaus H, Bhat B, Swayze EE, Seth PP. Egli M, et al. J Am Chem Soc. 2011 Oct 19;133(41):16642-9. doi: 10.1021/ja207086x. Epub 2011 Sep 22. J Am Chem Soc. 2011. PMID: 21919455 Free PMC article.

2

Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.

Tereshko V, Wilds CJ, Minasov G, Prakash TP, Maier MA, Howard A, Wawrzak Z, Manoharan M, Egli M. Tereshko V, et al. Among authors: egli m. Nucleic Acids Res. 2001 Mar 1;29(5):1208-15. doi: 10.1093/nar/29.5.1208. Nucleic Acids Res. 2001. PMID: 11222771 Free PMC article.

3

2'-O-[2-(methylthio)ethyl]-modified oligonucleotide: an analogue of 2'-O-[2-(methoxy)-ethyl]-modified oligonucleotide with improved protein binding properties and high binding affinity to target RNA.

Prakash TP, Manoharan M, Kawasaki AM, Fraser AS, Lesnik EA, Sioufi N, Leeds JM, Teplova M, Egli M. Prakash TP, et al. Among authors: egli m. Biochemistry. 2002 Oct 1;41(39):11642-8. doi: 10.1021/bi020264t. Biochemistry. 2002. PMID: 12269806

4

Crystal structure of a B-form DNA duplex containing (L)-alpha-threofuranosyl (3'-->2') nucleosides: a four-carbon sugar is easily accommodated into the backbone of DNA.

Wilds CJ, Wawrzak Z, Krishnamurthy R, Eschenmoser A, Egli M. Wilds CJ, et al. Among authors: egli m. J Am Chem Soc. 2002 Nov 20;124(46):13716-21. doi: 10.1021/ja0207807. J Am Chem Soc. 2002. PMID: 12431101

5

Selenium-assisted nucleic acid crystallography: use of phosphoroselenoates for MAD phasing of a DNA structure.

Wilds CJ, Pattanayek R, Pan C, Wawrzak Z, Egli M. Wilds CJ, et al. Among authors: egli m. J Am Chem Soc. 2002 Dec 18;124(50):14910-6. doi: 10.1021/ja021058b. J Am Chem Soc. 2002. PMID: 12475332

6

2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effects.

Prhavc M, Prakash TP, Minasov G, Cook PD, Egli M, Manoharan M. Prhavc M, et al. Among authors: egli m. Org Lett. 2003 Jun 12;5(12):2017-20. doi: 10.1021/ol0340991. Org Lett. 2003. PMID: 12790517

7

Face-to-face and edge-to-face pi-pi interactions in a synthetic DNA hairpin with a stilbenediether linker.

Egli M, Tereshko V, Mushudov GN, Sanishvili R, Liu X, Lewis FD. Egli M, et al. J Am Chem Soc. 2003 Sep 10;125(36):10842-9. doi: 10.1021/ja0355527. J Am Chem Soc. 2003. PMID: 12952463

8

Why does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis.

Pallan PS, Wilds CJ, Wawrzak Z, Krishnamurthy R, Eschenmoser A, Egli M. Pallan PS, et al. Among authors: egli m. Angew Chem Int Ed Engl. 2003;42(47):5893-5. doi: 10.1002/anie.200352553. Angew Chem Int Ed Engl. 2003. PMID: 14673929 No abstract available.

9

2'-O-[2-(guanidinium)ethyl]-modified oligonucleotides: stabilizing effect on duplex and triplex structures.

Prakash TP, Püschl A, Lesnik E, Mohan V, Tereshko V, Egli M, Manoharan M. Prakash TP, et al. Among authors: egli m. Org Lett. 2004 Jun 10;6(12):1971-4. doi: 10.1021/ol049470e. Org Lett. 2004. PMID: 15176796

10

Water-nucleobase "stacking": H-pi and lone pair-pi interactions in the atomic resolution crystal structure of an RNA pseudoknot.

Sarkhel S, Rich A, Egli M. Sarkhel S, et al. Among authors: egli m. J Am Chem Soc. 2003 Jul 30;125(30):8998-9. doi: 10.1021/ja0357801. J Am Chem Soc. 2003. PMID: 15369340

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