Kunapuli SP - Search Results

1

BF061, a novel antiplatelet and antithrombotic agent targeting P2Y₁₂ receptor and phosphodiesterase.

Hu L, Fan Z, Du H, Ni R, Zhang S, Yin K, Ye J, Zhang Y, Wei X, Zhang X, Gross PL, Kunapuli SP, Ding Z. Hu L, et al. Among authors: kunapuli sp. Thromb Haemost. 2011 Dec;106(6):1203-14. doi: 10.1160/TH11-06-0400. Epub 2011 Sep 22. Thromb Haemost. 2011. PMID: 21946947

2

Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues, Cys17 and Cys270.

Ding Z, Kim S, Dorsam RT, Jin J, Kunapuli SP. Ding Z, et al. Among authors: kunapuli sp. Blood. 2003 May 15;101(10):3908-14. doi: 10.1182/blood-2002-10-3027. Epub 2003 Jan 30. Blood. 2003. PMID: 12560222 Free article.

3

ADP receptors--targets for developing antithrombotic agents.

Kunapuli SP, Ding Z, Dorsam RT, Kim S, Murugappan S, Quinton TM. Kunapuli SP, et al. Curr Pharm Des. 2003;9(28):2303-16. doi: 10.2174/1381612033453947. Curr Pharm Des. 2003. PMID: 14529392 Review.

4

Molecular mechanism of nucleotide-induced primary granule release in human neutrophils: role for the P2Y2 receptor.

Meshki J, Tuluc F, Bredetean O, Ding Z, Kunapuli SP. Meshki J, et al. Among authors: kunapuli sp. Am J Physiol Cell Physiol. 2004 Feb;286(2):C264-71. doi: 10.1152/ajpcell.00287.2003. Epub 2003 Nov 12. Am J Physiol Cell Physiol. 2004. PMID: 14613890 Free article.

5

Clopidogrel: interactions with the P2Y12 receptor and clinical relevance.

Dorsam RT, Murugappan S, Ding Z, Kunapuli SP. Dorsam RT, et al. Among authors: kunapuli sp. Hematology. 2003 Dec;8(6):359-65. doi: 10.1080/10245330310001621260. Hematology. 2003. PMID: 14668029 Free article. Review. No abstract available.

6

Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses.

Shankar H, Murugappan S, Kim S, Jin J, Ding Z, Wickman K, Kunapuli SP. Shankar H, et al. Among authors: kunapuli sp. Blood. 2004 Sep 1;104(5):1335-43. doi: 10.1182/blood-2004-01-0069. Epub 2004 May 13. Blood. 2004. PMID: 15142872 Free article.

7

Identification of a potent inverse agonist at a constitutively active mutant of human P2Y12 receptor.

Ding Z, Kim S, Kunapuli SP. Ding Z, et al. Among authors: kunapuli sp. Mol Pharmacol. 2006 Jan;69(1):338-45. doi: 10.1124/mol.105.014654. Epub 2005 Oct 18. Mol Pharmacol. 2006. PMID: 16234484

8

P2Y12 receptor-mediated potentiation of thrombin-induced thromboxane A2 generation in platelets occurs through regulation of Erk1/2 activation.

Shankar H, Garcia A, Prabhakar J, Kim S, Kunapuli SP. Shankar H, et al. Among authors: kunapuli sp. J Thromb Haemost. 2006 Mar;4(3):638-47. doi: 10.1111/j.1538-7836.2006.01789.x. J Thromb Haemost. 2006. PMID: 16460446 Free article.

9

Studies on the role of the extracellular cysteines and oligomeric structures of the P2Y12 receptor when interacting with antagonists.

Ding Z, Bynagari YS, Mada SR, Jakubowski JA, Kunapuli SP. Ding Z, et al. Among authors: kunapuli sp. J Thromb Haemost. 2009 Jan;7(1):232-4. doi: 10.1111/j.1538-7836.2008.03202.x. Epub 2008 Oct 25. J Thromb Haemost. 2009. PMID: 18983481 Free article. No abstract available.

10

BF0801, a novel adenine derivative, inhibits platelet activation via phosphodiesterase inhibition and P2Y12 antagonism.

Zhang S, Hu L, Du H, Guo Y, Zhang Y, Niu H, Jin J, Zhang J, Liu J, Zhang X, Kunapuli SP, Ding Z. Zhang S, et al. Among authors: kunapuli sp. Thromb Haemost. 2010 Oct;104(4):845-57. doi: 10.1160/TH10-05-0285. Epub 2010 Aug 30. Thromb Haemost. 2010. PMID: 20806121

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