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A human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo.
Meuleman P, Catanese MT, Verhoye L, Desombere I, Farhoudi A, Jones CT, Sheahan T, Grzyb K, Cortese R, Rice CM, Leroux-Roels G, Nicosia A. Meuleman P, et al. Among authors: rice cm. Hepatology. 2012 Feb;55(2):364-72. doi: 10.1002/hep.24692. Epub 2011 Dec 16. Hepatology. 2012. PMID: 21953761 Free PMC article.
Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents.
Vercauteren K, Van Den Eede N, Mesalam AA, Belouzard S, Catanese MT, Bankwitz D, Wong-Staal F, Cortese R, Dubuisson J, Rice CM, Pietschmann T, Leroux-Roels G, Nicosia A, Meuleman P. Vercauteren K, et al. Among authors: rice cm. Hepatology. 2014 Nov;60(5):1508-18. doi: 10.1002/hep.27196. Epub 2014 Jul 30. Hepatology. 2014. PMID: 24797654 Free PMC article.
High-avidity monoclonal antibodies against the human scavenger class B type I receptor efficiently block hepatitis C virus infection in the presence of high-density lipoprotein.
Catanese MT, Graziani R, von Hahn T, Moreau M, Huby T, Paonessa G, Santini C, Luzzago A, Rice CM, Cortese R, Vitelli A, Nicosia A. Catanese MT, et al. Among authors: rice cm. J Virol. 2007 Aug;81(15):8063-71. doi: 10.1128/JVI.00193-07. Epub 2007 May 16. J Virol. 2007. PMID: 17507483 Free PMC article.
A genetically humanized mouse model for hepatitis C virus infection.
Dorner M, Horwitz JA, Robbins JB, Barry WT, Feng Q, Mu K, Jones CT, Schoggins JW, Catanese MT, Burton DR, Law M, Rice CM, Ploss A. Dorner M, et al. Among authors: rice cm. Nature. 2011 Jun 8;474(7350):208-11. doi: 10.1038/nature10168. Nature. 2011. PMID: 21654804 Free PMC article.
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro.
Lindenbach BD, Meuleman P, Ploss A, Vanwolleghem T, Syder AJ, McKeating JA, Lanford RE, Feinstone SM, Major ME, Leroux-Roels G, Rice CM. Lindenbach BD, et al. Among authors: rice cm. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3805-9. doi: 10.1073/pnas.0511218103. Epub 2006 Feb 16. Proc Natl Acad Sci U S A. 2006. PMID: 16484368 Free PMC article.
701 results