Hutchinson MR - Search Results

1

Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice.

Wu Y, Lousberg EL, Moldenhauer LM, Hayball JD, Coller JK, Rice KC, Watkins LR, Somogyi AA, Hutchinson MR. Wu Y, et al. Among authors: hutchinson mr. Br J Pharmacol. 2012 Mar;165(5):1319-29. doi: 10.1111/j.1476-5381.2011.01572.x. Br J Pharmacol. 2012. PMID: 21955045 Free PMC article.

2

Diacetylmorphine degradation to 6-monoacetylmorphine and morphine in cell culture: implications for in vitro studies.

Hutchinson MR, Somogyi AA. Hutchinson MR, et al. Eur J Pharmacol. 2002 Oct 18;453(1):27-32. doi: 10.1016/s0014-2999(02)02365-8. Eur J Pharmacol. 2002. PMID: 12393056

3

Quantification of the O- and N-demethylated metabolites of hydrocodone and oxycodone in human liver microsomes using liquid chromatography with ultraviolet absorbance detection.

Menelaou A, Hutchinson MR, Quinn I, Christensen A, Somogyi AA. Menelaou A, et al. Among authors: hutchinson mr. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Feb 25;785(1):81-8. doi: 10.1016/s1570-0232(02)00856-5. J Chromatogr B Analyt Technol Biomed Life Sci. 2003. PMID: 12535841

4

CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes.

Hutchinson MR, Menelaou A, Foster DJ, Coller JK, Somogyi AA. Hutchinson MR, et al. Br J Clin Pharmacol. 2004 Mar;57(3):287-97. doi: 10.1046/j.1365-2125.2003.02002.x. Br J Clin Pharmacol. 2004. PMID: 14998425 Free PMC article.

5

Relationship between 4,5-epoxymorphinan structure and in vitro modulation of cell proliferation.

Hutchinson MR, Somogyi AA. Hutchinson MR, et al. Eur J Pharmacol. 2004 Jun 28;494(2-3):251-62. doi: 10.1016/j.ejphar.2004.04.049. Eur J Pharmacol. 2004. PMID: 15212982

6

In vitro opioid induced proliferation of peripheral blood immune cells correlates with in vivo cold pressor pain tolerance in humans: a biological marker of pain tolerance.

Hutchinson MR, La Vincente SF, Somogyi AA. Hutchinson MR, et al. Pain. 2004 Aug;110(3):751-755. doi: 10.1016/j.pain.2004.05.017. Pain. 2004. PMID: 15288416

7

(S)-(+)-methadone is more immunosuppressive than the potent analgesic (R)-(--)-methadone.

Hutchinson MR, Somogyi AA. Hutchinson MR, et al. Int Immunopharmacol. 2004 Nov;4(12):1525-30. doi: 10.1016/j.intimp.2004.07.011. Int Immunopharmacol. 2004. PMID: 15351321

8

Characterisation of the in vitro modulation of splenocyte proliferation by non-4,5-epoxymorphinan opioids.

Hutchinson MR, Somogyi AA. Hutchinson MR, et al. Int Immunopharmacol. 2005 Nov;5(12):1713-22. doi: 10.1016/j.intimp.2005.05.006. Int Immunopharmacol. 2005. PMID: 16102521

9

Glia: novel counter-regulators of opioid analgesia.

Watkins LR, Hutchinson MR, Johnston IN, Maier SF. Watkins LR, et al. Among authors: hutchinson mr. Trends Neurosci. 2005 Dec;28(12):661-9. doi: 10.1016/j.tins.2005.10.001. Epub 2005 Oct 24. Trends Neurosci. 2005. PMID: 16246435 Review.

10

Norman Cousins Lecture. Glia as the "bad guys": implications for improving clinical pain control and the clinical utility of opioids.

Watkins LR, Hutchinson MR, Ledeboer A, Wieseler-Frank J, Milligan ED, Maier SF. Watkins LR, et al. Among authors: hutchinson mr. Brain Behav Immun. 2007 Feb;21(2):131-46. doi: 10.1016/j.bbi.2006.10.011. Epub 2006 Dec 18. Brain Behav Immun. 2007. PMID: 17175134 Free PMC article.

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