Witcher M - Search Results

1

Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.

DiTacchio L, Le HD, Vollmers C, Hatori M, Witcher M, Secombe J, Panda S. DiTacchio L, et al. Among authors: witcher m. Science. 2011 Sep 30;333(6051):1881-5. doi: 10.1126/science.1206022. Science. 2011. PMID: 21960634 Free PMC article.

2

Genome-wide targeting of the epigenetic regulatory protein CTCF to gene promoters by the transcription factor TFII-I.

Peña-Hernández R, Marques M, Hilmi K, Zhao T, Saad A, Alaoui-Jamali MA, del Rincon SV, Ashworth T, Roy AL, Emerson BM, Witcher M. Peña-Hernández R, et al. Among authors: witcher m. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E677-86. doi: 10.1073/pnas.1416674112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646466 Free PMC article.

3

Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary.

Witcher M, Emerson BM. Witcher M, et al. Mol Cell. 2009 May 15;34(3):271-84. doi: 10.1016/j.molcel.2009.04.001. Mol Cell. 2009. PMID: 19450526 Free PMC article.

4

Functional and molecular characterization of the role of CTCF in human embryonic stem cell biology.

Balakrishnan SK, Witcher M, Berggren TW, Emerson BM. Balakrishnan SK, et al. Among authors: witcher m. PLoS One. 2012;7(8):e42424. doi: 10.1371/journal.pone.0042424. Epub 2012 Aug 3. PLoS One. 2012. PMID: 22879976 Free PMC article.

5

Analysis of changes to mRNA levels and CTCF occupancy upon TFII-I knockdown.

Marques M, Hernández RP, Witcher M. Marques M, et al. Among authors: witcher m. Genom Data. 2014 Oct 18;4:17-21. doi: 10.1016/j.gdata.2014.09.012. eCollection 2015 Jun. Genom Data. 2014. PMID: 26484167 Free PMC article.

6

Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2.

Saad A, Bijian K, Qiu D, da Silva SD, Marques M, Chang CH, Nassour H, Ramotar D, Damaraju S, Mackey J, Bismar T, Witcher M, Alaoui-Jamali MA. Saad A, et al. Among authors: witcher m. Sci Rep. 2016 Nov 7;6:36699. doi: 10.1038/srep36699. Sci Rep. 2016. PMID: 27819326 Free PMC article.

7

CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair.

Hilmi K, Jangal M, Marques M, Zhao T, Saad A, Zhang C, Luo VM, Syme A, Rejon C, Yu Z, Krum A, Fabian MR, Richard S, Alaoui-Jamali M, Orthwein A, McCaffrey L, Witcher M. Hilmi K, et al. Among authors: witcher m. Sci Adv. 2017 May 24;3(5):e1601898. doi: 10.1126/sciadv.1601898. eCollection 2017 May. Sci Adv. 2017. PMID: 28560323 Free PMC article.

8

SWI/SNF-Compromised Cancers Are Susceptible to Bromodomain Inhibitors.

Shorstova T, Marques M, Su J, Johnston J, Kleinman CL, Hamel N, Huang S, Alaoui-Jamali MA, Foulkes WD, Witcher M. Shorstova T, et al. Among authors: witcher m. Cancer Res. 2019 May 15;79(10):2761-2774. doi: 10.1158/0008-5472.CAN-18-1545. Epub 2019 Mar 15. Cancer Res. 2019. PMID: 30877105

9

Reprogramming of Nucleotide Metabolism Mediates Synergy between Epigenetic Therapy and MAP Kinase Inhibition.

Shorstova T, Su J, Zhao T, Dahabieh M, Leibovitch M, De Sa Tavares Russo M, Avizonis D, Rajkumar S, Watson IR, Del Rincón SV, Miller WH Jr, Foulkes WD, Witcher M. Shorstova T, et al. Among authors: witcher m. Mol Cancer Ther. 2021 Jan;20(1):64-75. doi: 10.1158/1535-7163.MCT-20-0259. Epub 2020 Oct 21. Mol Cancer Ther. 2021. PMID: 33087508

10

Gallotannin imposes S phase arrest in breast cancer cells and suppresses the growth of triple-negative tumors in vivo.

Zhao T, Sun Q, del Rincon SV, Lovato A, Marques M, Witcher M. Zhao T, et al. Among authors: witcher m. PLoS One. 2014 Mar 21;9(3):e92853. doi: 10.1371/journal.pone.0092853. eCollection 2014. PLoS One. 2014. PMID: 24658335 Free PMC article.

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