Kapanen AI - Search Results

1

The combination of gefitinib and RAD001 inhibits growth of HER2 overexpressing breast cancer cells and tumors irrespective of trastuzumab sensitivity.

Dragowska WH, Weppler SA, Qadir MA, Wong LY, Franssen Y, Baker JH, Kapanen AI, Kierkels GJ, Masin D, Minchinton AI, Gelmon KA, Bally MB. Dragowska WH, et al. Among authors: kapanen ai. BMC Cancer. 2011 Oct 1;11:420. doi: 10.1186/1471-2407-11-420. BMC Cancer. 2011. PMID: 21961653 Free PMC article.

2

Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer.

Dragowska WH, Weppler SA, Wang JC, Wong LY, Kapanen AI, Rawji JS, Warburton C, Qadir MA, Donohue E, Roberge M, Gorski SM, Gelmon KA, Bally MB. Dragowska WH, et al. Among authors: kapanen ai. PLoS One. 2013 Oct 11;8(10):e76503. doi: 10.1371/journal.pone.0076503. eCollection 2013. PLoS One. 2013. PMID: 24146879 Free PMC article.

3

Silencing Bcl-2 in models of mantle cell lymphoma is associated with decreases in cyclin D1, nuclear factor-kappaB, p53, bax, and p27 levels.

Tucker CA, Kapanen AI, Chikh G, Hoffman BG, Kyle AH, Wilson IM, Masin D, Gascoyne RD, Bally M, Klasa RJ. Tucker CA, et al. Among authors: kapanen ai. Mol Cancer Ther. 2008 Apr;7(4):749-58. doi: 10.1158/1535-7163.MCT-07-0302. Epub 2008 Mar 28. Mol Cancer Ther. 2008. PMID: 18375822

4

Modulation of cancer cell survival pathways using multivalent liposomal therapeutic antibody constructs.

Chiu GN, Edwards LA, Kapanen AI, Malinen MM, Dragowska WH, Warburton C, Chikh GG, Fang KY, Tan S, Sy J, Tucker C, Waterhouse DN, Klasa R, Bally MB. Chiu GN, et al. Among authors: kapanen ai. Mol Cancer Ther. 2007 Mar;6(3):844-55. doi: 10.1158/1535-7163.MCT-06-0159. Epub 2007 Mar 5. Mol Cancer Ther. 2007. PMID: 17339368 Free article.

5

Multivalent rituximab lipid nanoparticles as improved lymphoma therapies: indirect mechanisms of action and in vivo activity.

Popov J, Kapanen AI, Turner C, Ng R, Tucker C, Chiu G, Klasa R, Bally MB, Chikh G. Popov J, et al. Among authors: kapanen ai. Nanomedicine (Lond). 2011 Nov;6(9):1575-91. doi: 10.2217/nnm.11.50. Epub 2011 Oct 20. Nanomedicine (Lond). 2011. PMID: 22011314

6

Development of a liposomal nanoparticle formulation of 5-fluorouracil for parenteral administration: formulation design, pharmacokinetics and efficacy.

Thomas AM, Kapanen AI, Hare JI, Ramsay E, Edwards K, Karlsson G, Bally MB. Thomas AM, et al. Among authors: kapanen ai. J Control Release. 2011 Mar 10;150(2):212-9. doi: 10.1016/j.jconrel.2010.11.018. Epub 2010 Nov 19. J Control Release. 2011. PMID: 21094191

7

Characterization of a novel cell line established from a patient with Herceptin-resistant breast cancer.

Tanner M, Kapanen AI, Junttila T, Raheem O, Grenman S, Elo J, Elenius K, Isola J. Tanner M, et al. Among authors: kapanen ai. Mol Cancer Ther. 2004 Dec;3(12):1585-92. Mol Cancer Ther. 2004. PMID: 15634652

8

Trastuzumab causes antibody-dependent cellular cytotoxicity-mediated growth inhibition of submacroscopic JIMT-1 breast cancer xenografts despite intrinsic drug resistance.

Barok M, Isola J, Pályi-Krekk Z, Nagy P, Juhász I, Vereb G, Kauraniemi P, Kapanen A, Tanner M, Vereb G, Szöllösi J. Barok M, et al. Mol Cancer Ther. 2007 Jul;6(7):2065-72. doi: 10.1158/1535-7163.MCT-06-0766. Mol Cancer Ther. 2007. PMID: 17620435

9

Decreased accessibility and lack of activation of ErbB2 in JIMT-1, a herceptin-resistant, MUC4-expressing breast cancer cell line.

Nagy P, Friedländer E, Tanner M, Kapanen AI, Carraway KL, Isola J, Jovin TM. Nagy P, et al. Among authors: kapanen ai. Cancer Res. 2005 Jan 15;65(2):473-82. Cancer Res. 2005. PMID: 15695389

10

Cytogenetic characterization and gene expression profiling of the trastuzumab-resistant breast cancer cell line JIMT-1.

Rennstam K, Jönsson G, Tanner M, Bendahl PO, Staaf J, Kapanen AI, Karhu R, Baldetorp B, Borg A, Isola J. Rennstam K, et al. Among authors: kapanen ai. Cancer Genet Cytogenet. 2007 Jan 15;172(2):95-106. doi: 10.1016/j.cancergencyto.2006.09.014. Cancer Genet Cytogenet. 2007. PMID: 17213017

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