Zhai RG - Search Results

1

NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy.

Ali YO, Ruan K, Zhai RG. Ali YO, et al. Among authors: zhai rg. Hum Mol Genet. 2012 Jan 15;21(2):237-50. doi: 10.1093/hmg/ddr449. Epub 2011 Sep 30. Hum Mol Genet. 2012. PMID: 21965302 Free PMC article.

2

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration.

Zhai RG, Zhang F, Hiesinger PR, Cao Y, Haueter CM, Bellen HJ. Zhai RG, et al. Nature. 2008 Apr 17;452(7189):887-91. doi: 10.1038/nature06721. Epub 2008 Mar 16. Nature. 2008. PMID: 18344983 Free PMC article.

3

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme.

Zhai RG, Rizzi M, Garavaglia S. Zhai RG, et al. Cell Mol Life Sci. 2009 Sep;66(17):2805-18. doi: 10.1007/s00018-009-0047-x. Epub 2009 May 16. Cell Mol Life Sci. 2009. PMID: 19448972 Free PMC article. Review.

4

Dealing with misfolded proteins: examining the neuroprotective role of molecular chaperones in neurodegeneration.

Ali YO, Kitay BM, Zhai RG. Ali YO, et al. Among authors: zhai rg. Molecules. 2010 Oct 8;15(10):6859-87. doi: 10.3390/molecules15106859. Molecules. 2010. PMID: 20938400 Free PMC article. Review.

5

Assaying locomotor, learning, and memory deficits in Drosophila models of neurodegeneration.

Ali YO, Escala W, Ruan K, Zhai RG. Ali YO, et al. Among authors: zhai rg. J Vis Exp. 2011 Mar 11;(49):2504. doi: 10.3791/2504. J Vis Exp. 2011. PMID: 21445036 Free PMC article.

6

Nicotinamide mononucleotide adenylyltransferase is a stress response protein regulated by the heat shock factor/hypoxia-inducible factor 1alpha pathway.

Ali YO, McCormack R, Darr A, Zhai RG. Ali YO, et al. Among authors: zhai rg. J Biol Chem. 2011 May 27;286(21):19089-99. doi: 10.1074/jbc.M111.219295. Epub 2011 Apr 8. J Biol Chem. 2011. PMID: 21478149 Free PMC article.

7

Nmnat exerts neuroprotective effects in dendrites and axons.

Wen Y, Parrish JZ, He R, Zhai RG, Kim MD. Wen Y, et al. Among authors: zhai rg. Mol Cell Neurosci. 2011 Sep;48(1):1-8. doi: 10.1016/j.mcn.2011.05.002. Epub 2011 May 9. Mol Cell Neurosci. 2011. PMID: 21596138 Free PMC article.

8

CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy.

Ljungberg MC, Ali YO, Zhu J, Wu CS, Oka K, Zhai RG, Lu HC. Ljungberg MC, et al. Among authors: zhai rg. Hum Mol Genet. 2012 Jan 15;21(2):251-67. doi: 10.1093/hmg/ddr492. Epub 2011 Oct 25. Hum Mol Genet. 2012. PMID: 22027994 Free PMC article.

9

Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini.

Ouyang H, Ali YO, Ravichandran M, Dong A, Qiu W, MacKenzie F, Dhe-Paganon S, Arrowsmith CH, Zhai RG. Ouyang H, et al. Among authors: zhai rg. J Biol Chem. 2012 Jan 20;287(4):2317-27. doi: 10.1074/jbc.M111.273730. Epub 2011 Nov 8. J Biol Chem. 2012. PMID: 22069321 Free PMC article.

10

Nicotinamide mononucleotide adenylyltransferase maintains active zone structure by stabilizing Bruchpilot.

Zang S, Ali YO, Ruan K, Zhai RG. Zang S, et al. Among authors: zhai rg. EMBO Rep. 2013 Jan;14(1):87-94. doi: 10.1038/embor.2012.181. Epub 2012 Nov 16. EMBO Rep. 2013. PMID: 23154466 Free PMC article.

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