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A high-throughput single-cell analysis of human CD8⁺ T cell functions reveals discordance for cytokine secretion and cytolysis.
Varadarajan N, Julg B, Yamanaka YJ, Chen H, Ogunniyi AO, McAndrew E, Porter LC, Piechocka-Trocha A, Hill BJ, Douek DC, Pereyra F, Walker BD, Love JC. Varadarajan N, et al. Among authors: douek dc. J Clin Invest. 2011 Nov;121(11):4322-31. doi: 10.1172/JCI58653. Epub 2011 Oct 3. J Clin Invest. 2011. PMID: 21965332 Free PMC article.
HIV preferentially infects HIV-specific CD4+ T cells.
Douek DC, Brenchley JM, Betts MR, Ambrozak DR, Hill BJ, Okamoto Y, Casazza JP, Kuruppu J, Kunstman K, Wolinsky S, Grossman Z, Dybul M, Oxenius A, Price DA, Connors M, Koup RA. Douek DC, et al. Nature. 2002 May 2;417(6884):95-8. doi: 10.1038/417095a. Nature. 2002. PMID: 11986671
456 results